Evidence map›Paper›PMID 36617063›Full record

ArticleSensors (Basel, Switzerland)2023

Investigation of GOx Stability in a Chitosan Matrix: Applications for Enzymatic Electrodes.

Ayman Chmayssem, Ibrahim Shalayel, Stéphane Marinesco, Abdelkader Zebda

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayman ChmayssemUniversité Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, INSERM, TIMC, 38000 Grenoble, France.ORCID 0000-0002-2831-2626
Ibrahim ShalayelUniversité Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, INSERM, TIMC, 38000 Grenoble, France.ORCID 0000-0001-9368-3565
Stéphane MarinescoPlate-Forme Technologique BELIV, Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, Université Claude Bernard Lyon 1, 69373 Lyon, France.
Abdelkader ZebdaUniversité Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, INSERM, TIMC, 38000 Grenoble, France.

Funding

Campus France PHC POLONIUM 2021 programFrench National Centre for Scientific Research MITI 2022Institut Carnot LSI BIOEPC 2022
6 · The paper itself

Abstract

In this study, we designed a new biosensing membrane for the development of an electrochemical glucose biosensor. To proceed, we used a chitosan-based hydrogel that entraps glucose oxidase enzyme (GOx), and we crosslinked the whole matrix using glutaraldehyde, which is known for its quick and reactive crosslinking behavior. Then, the stability of the designed biosensors was investigated over time, according to different storage conditions (in PBS solution at temperatures of 4 °C and 37 °C and in the presence or absence of glucose). In some specific conditions, we found that our biosensor is capable of maintaining its stability for more than six months of storage. We also included catalase to protect the biosensing membranes from the enzymatic reaction by-products (e.g., hydrogen peroxide). This design protects the biocatalytic activity of GOx and enhances the lifetime of the biosensor.

Indexed as

Biosensing TechniquesChitosanElectrodesEnzymes, ImmobilizedGlucoseGlucose OxidaseChitosanEnzymes, ImmobilizedGlucoseGlucose Oxidasechitosan matrixglucose biosensorglucose oxidase (GOx)glutaraldehyde crosslinkerscreen-printed electrode

Identifiers

PMID36617063
PMCPMC9824325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.