Evidence map›Paper›PMID 36616654›Full record

ArticleSensors (Basel, Switzerland)2022

Phase Contrast Image-Based Rapid Antimicrobial Susceptibility Testing of Bacteria in Liquid Culture Media.

Xiaonan Zhang, Xuenian Wang, Yaqing Bao, Zhiyuan Shen, Yang Xu, Bei Wang, Haowei Zhang, Tian Guan, Yonghong He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xiaonan ZhangSchool of Medicine, Tsinghua University, Beijing 100084, China.
Xuenian WangInstitute of Optical Imaging and Sensing, Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Yaqing BaoGBA Center for Medical Device Evaluation and Inspection, National Medical Products Administration, Shenzhen 518045, China.
Zhiyuan ShenMedical Optical Technology R&D Center, Research Institute of Tsinghua, Pearl River Delta, Guangzhou 510700, China.
Yang XuInstitute of Optical Imaging and Sensing, Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Bei WangInstitute of Optical Imaging and Sensing, Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Haowei ZhangSchool of Life Sciences, Tsinghua University, Beijing 100084, China.
Tian GuanSchool of Medicine, Tsinghua University, Beijing 100084, China.
Yonghong HeInstitute of Optical Imaging and Sensing, Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Tsinghua University · CNUniversity Town of Shenzhen · CNNational Medical Products Administration · CN

Funding

National Natural Science Foundation of China 61875102, 62005142Science and Technology Research Program of Shenzhen City JCYJ20200109110606054， WDZC20200821141349001Tsinghua University Spring Breeze Fund 2020Z99CFZ023
6 · The paper itself

Abstract

Currently, the world is facing the problem of bacterial resistance, which threatens public health, and bacterial antimicrobial susceptibility testing (AST) plays an important role in biomedicine, dietary safety and aquaculture. Traditional AST methods take a long time, usually 16-24 h, and cannot meet the demand for rapid diagnosis in the clinic, so rapid AST methods are needed to shorten the detection time. In this study, by using an in-house built centrifuge to centrifuge bacteria in a liquid medium onto the inner wall of the bottom surface of a counting plate, and using a phase contrast microscope to track bacterial growth under the effect of different antibiotic concentrations, the results of the minimum inhibitory concentration (MIC) of bacteria under the effect of antibiotics can be obtained in as early as 4 h. We used a combination of

Indexed as

Anti-Bacterial AgentsEscherichia coliBacteriaCulture MediaMicrobial Sensitivity TestsAnti-Bacterial AgentsCulture MediabacteriaMICphase contrast microscoperapid AST

Identifiers

PMID36616654
PMCPMC9824109
OpenAlexW4312186599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.