Evidence map›Paper›PMID 36616572›Full record

ArticlePolymers2022

PCL/Collagen/UA Composite Biomedical Dressing with Ordered Microfiberous Structure Fabricated by a 3D Near-Field Electrospinning Process.

Zhirui Mai, Qilong Liu, Yongshuang Bian, Peng Wang, Xuewei Fu, Dongsong Lin, Nianzi Kong, Yuqing Huang, Zijun Zeng, Dingfan Li and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Usnic Acid and Its Topical Use-A Concise Review.Molecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Harnessing Nanocarriers to Advance Vaccine Development.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Zhirui MaiKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Qilong LiuKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Yongshuang BianKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Peng WangGraduate School of Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Xuewei FuKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Dongsong LinKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Nianzi KongDepartment of Pharmaceutical Engineering, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Yuqing HuangDepartment of Pharmaceutical Engineering, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Zijun ZengKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Dingfan LiKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Wenxu ZhengKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Yuanjun XiaGuangdong Key Lab of Orthopedic Technology and Implant Materials, Department of Orthopaedics, General Hospital of Southern Theater Command of PLA, The First School of Clinical Medicine of Southern Medical University, Guangzhou 510010, China.
Wuyi ZhouKey Laboratory for Biobased Materials and Energy of Ministry of Education, Biomass 3D Printing Materials Research Center, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-8874-4084
South China Agricultural University · CNGuangzhou University of Chinese Medicine · CNSouthern Medical University · CN

Funding

Innovation Team Project of Shaoguang City 2019Nanning Local Scientific Research and Technology Development Plan Project 20213122the Science and Technology Foundation of Guangdong Province 2020A0505100050the Science and Technology Foundation of Guangdong Province 2020A1515011004University Teachers Innovation Research Project 2021SWYY04
6 · The paper itself

Abstract

In this work, a functionalized polycaprolactone (PCL) composite fiber combining calf-type I collagen (CO) and natural drug usnic acid (UA) was prepared, in which UA was used as an antibacterial agent. Through 3D near-field electrospinning, the mixed solution was prepared into PCL/CO/UA composite fibers (PCUCF), which has a well-defined perfect arrangement structure. The influence of electrospinning process parameters on fiber diameter was investigated, the optimal electrospinning parameters were determined, and the electric field simulation was conducted to verify the optimal parameters. The addition of 20% collagen made the composite fiber have good hydrophilicity and water absorption property. In the presence of PCUCF, 1% UA content significantly inhibited the growth rate of Gram-positive and negative bacteria in the plate culture. The AC-PCUCF (after crosslinking PCUCF) prepared by crosslinking collagen with genipin showed stronger mechanical properties, water absorption property, thermal stability, and drug release performance. Cell proliferation experiments showed that PCUCF and AC-PCUCF had no cytotoxicity and could promote cell proliferation and adhesion. The results show that PCL/CO/UA composite fiber has potential application prospects in biomedical dressing.

Indexed as

antibacterialbiomedical dressingcollagennear-field electrospinning

Identifiers

PMID36616572
PMCPMC9824864
OpenAlexW4313471500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.