Evidence map›Paper›PMID 36616529›Full record

ArticlePolymers2022

Multifunctional Nanoparticles as High-Efficient Targeted Hypericin System for Theranostic Melanoma.

Flávia Amanda Pedroso de Morais, Ana Carolina Vieira De Oliveira, Rodolfo Bento Balbinot, Danielle Lazarin-Bidóia, Tânia Ueda-Nakamura, Sueli de Oliveira Silva, Katieli da Silva Souza Campanholi, Ranulfo Combuca da Silva Junior, Renato Sonchini Gonçalves, Wilker Caetano and 1 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Diverse Therapeutic Potentials of Hypericin: An In-Depth Review.Current topics in medicinal chemistry · 2025
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Flávia Amanda Pedroso de MoraisTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.ORCID 0000-0003-0208-6752
Ana Carolina Vieira De OliveiraDepartment of Chemistry, State University of Maringá, Maringá 87020-900, PR, Brazil.
Rodolfo Bento BalbinotTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.ORCID 0000-0001-8245-0950
Danielle Lazarin-BidóiaTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.
Tânia Ueda-NakamuraTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.
Sueli de Oliveira SilvaTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.ORCID 0000-0001-9303-0804
Katieli da Silva Souza CampanholiDepartment of Chemistry, State University of Maringá, Maringá 87020-900, PR, Brazil.ORCID 0000-0001-5156-8542
Ranulfo Combuca da Silva JuniorDepartment of Chemistry, State University of Maringá, Maringá 87020-900, PR, Brazil.
Renato Sonchini GonçalvesLaboratory of Chemistry of Natural Products, Department of Chemistry, Center for Exact Sciences and Technology, Federal University of Maranhão, São Luís 65080-805, MA, Brazil.ORCID 0000-0003-2701-6101
Wilker CaetanoDepartment of Chemistry, State University of Maringá, Maringá 87020-900, PR, Brazil.
Celso Vataru NakamuraTechnological Innovation Laboratory in the Pharmaceuticals and Cosmetics Development, State University of Maringá, Maringá 87020-900, PR, Brazil.
Universidade Estadual de Maringá · BRUniversidade Federal do Maranhão · BR

Funding

National Council for Scientific and Technological Development 162876/2020-3
6 · The paper itself

Abstract

Biotin, spermine, and folic acid were covalently linked to the F127 copolymer to obtain a new drug delivery system designed for HY-loaded PDT treatment against B

Indexed as

biotinfolatehypericinmultifunctional micellesphotodynamic therapyspermine

Identifiers

PMID36616529
PMCPMC9824163
OpenAlexW4313362035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.