Evidence map›Paper›PMID 36616422›Full record

ArticlePolymers2022

Polylactic Acid/Polyaniline Nanofibers Subjected to Pre- and Post-Electrospinning Plasma Treatments for Refined Scaffold-Based Nerve Tissue Engineering Applications.

Yongjian Guo, Rouba Ghobeira, Sheida Aliakbarshirazi, Rino Morent, Nathalie De Geyter

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yongjian GuoDepartment of Applied Physics, Research Unit Plasma Technology (RUPT), Faculty of Engineering & Architecture, Ghent University, Sint-Pietersnieuwstraat 41, B4, 9000 Ghent, Belgium.ORCID 0000-0002-0804-0432
Rouba GhobeiraDepartment of Applied Physics, Research Unit Plasma Technology (RUPT), Faculty of Engineering & Architecture, Ghent University, Sint-Pietersnieuwstraat 41, B4, 9000 Ghent, Belgium.
Sheida AliakbarshiraziDepartment of Applied Physics, Research Unit Plasma Technology (RUPT), Faculty of Engineering & Architecture, Ghent University, Sint-Pietersnieuwstraat 41, B4, 9000 Ghent, Belgium.
Rino MorentDepartment of Applied Physics, Research Unit Plasma Technology (RUPT), Faculty of Engineering & Architecture, Ghent University, Sint-Pietersnieuwstraat 41, B4, 9000 Ghent, Belgium.
Nathalie De GeyterDepartment of Applied Physics, Research Unit Plasma Technology (RUPT), Faculty of Engineering & Architecture, Ghent University, Sint-Pietersnieuwstraat 41, B4, 9000 Ghent, Belgium.ORCID 0000-0001-7883-5786
Ghent University · BE

Funding

China Scholarship Council 201806220071Research Foundation Flanders-Belgium No. 12ZC720N
6 · The paper itself

Abstract

Composite biopolymer/conducting polymer scaffolds, such as polylactic acid (PLA)/ polyaniline (PAni) nanofibers, have emerged as popular alternative scaffolds in the electrical-sensitive nerve tissue engineering (TE). Although mimicking the extracellular matrix geometry, such scaffolds are highly hydrophobic and usually present an inhomogeneous morphology with massive beads that impede nerve cell-material interactions. Therefore, the present study launches an exclusive combinatorial strategy merging successive pre- and post-electrospinning plasma treatments to cope with these issues. Firstly, an atmospheric pressure plasma jet (APPJ) treatment was applied on PLA and PLA/PAni solutions prior to electrospinning, enhancing their viscosity and conductivity. These liquid property changes largely eliminated the beaded structures on the nanofibers, leading to uniform and nicely elongated fibers having average diameters between 170 and 230 nm. After electrospinning, the conceived scaffolds were subjected to a N

Indexed as

APPJ plasma treatmentDBD plasma treatmentnanofibersneurite extensionPC-12 cellsPLA/PAni

Identifiers

PMID36616422
PMCPMC9824446
OpenAlexW4312204185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.