Synthesis of fluorescent Molecularly Imprinted Polymer Nanoparticles Sensing Small Neurotransmitters with High Selectivity Using Immobilized Templates with Regulated Surface Density.

Yasuo Yoshimi, Yuto Katsumata, Naoya Osawa, Neo Ogishita, Ryota Kadoya

Abstract read

In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Molecular imprinting for neurology: Materials, applications, and limitations.Ibrain · 2026
Review
A Poly(methacrolein-Nanomaterials (Basel, Switzerland) · 2025
Article

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5 · Who and what money

Authors and funding

5 authors.

Yasuo YoshimiDepartment of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-Ku, Tokyo 135-8548, Japan.ORCID 0000-0002-5529-2720

Yuto KatsumataDepartment of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-Ku, Tokyo 135-8548, Japan.

Naoya OsawaDepartment of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-Ku, Tokyo 135-8548, Japan.

Neo OgishitaDepartment of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-Ku, Tokyo 135-8548, Japan.

Ryota KadoyaDepartment of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-Ku, Tokyo 135-8548, Japan.

Funding

Foundation for Promotion of Material Science Technology of Japan (2017). No numberJapan Society for the Promotion of Science 17H02088

6 · The paper itself

Abstract

To develop nanosensors to probe neurotransmitters, we synthesized fluorescent-functionalized molecularly imprinted polymeric nanoparticles (fMIP-NPs) using monoamine neurotransmitters (serotonin and dopamine) immobilized on glass beads as templates. The size and fluorescence intensity of the fMIP-NPs synthesized with blended silane couplers increased with the presence of the target but were insensitive to the target analogs (L-tryptophan and L-dopa, respectively). However, when the template is anchored by a pure silane agent, both the fluorescence intensity and particle size of the fMIP-NPs were sensitive to the structural analog of the template. Another fMIP-NP was synthesized in the presence of poly([2-(methacryloyloxy)ethyl] trimethylammonium chloride (METMAC)-

Indexed as

acetylcholinedopaminefluorescencemolecularly imprinted polymer (MIP)serotoninsolid phase synthesis

Identifiers

PMID36616121

DOI10.3390/nano13010212

PMCPMC9824157

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