Evidence map›Paper›PMID 36616081›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Supramolecular Hydrogels from a Tripeptide and Carbon Nano-Onions for Biological Applications.

Davide Marin, Michał Bartkowski, Slavko Kralj, Beatrice Rosetti, Paola D'Andrea, Simone Adorinni, Silvia Marchesan, Silvia Giordani

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davide MarinChemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-5130-2031
Michał BartkowskiSchool of Chemical Sciences, Faculty of Science & Health, Dublin City University, D09 E432 Dublin, Ireland.ORCID 0000-0002-0259-0919
Slavko KraljDepartment for Materials Synthesis, Jožef Stefan Institute, 1000 Ljubljana, Slovenia.ORCID 0000-0002-0771-3818
Beatrice RosettiChemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-4303-8407
Paola D'AndreaDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Simone AdorinniChemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-6888-7635
Silvia MarchesanChemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-6089-3873
Silvia GiordaniSchool of Chemical Sciences, Faculty of Science & Health, Dublin City University, D09 E432 Dublin, Ireland.ORCID 0000-0002-9212-5067

Funding

Irish Research Council GOIPG/2019/1820Slovenian Research Agency BI-FR/23-24-PROTEUS-005Slovenian Research Agency J2-3034Slovenian Research Agency J2-3040Slovenian Research Agency J2-3046Slovenian Research Agency J3-3079Slovenian Research Agency J7-4420Slovenian Research Agency P2-0089University of Trieste FRA2022
6 · The paper itself

Abstract

Nanocomposite hydrogels have attracted researchers' attention in recent years to achieve superior performances in a variety of materials applications. In this work, we describe the outcome of three different strategies to combine a self-assembling tripeptide and carbon nano-onions (CNOs), through covalent and non-covalent approaches, into supramolecular and nanostructured hydrogels. Importantly, the tripeptide coated the nano-onions and extended their aqueous dispersions' stability by several hours. Furthermore, CNOs could be loaded in the tripeptide hydrogels at the highest level ever reported for nanocarbons, indicating high compatibility between the components. The materials were formed in phosphate-buffered solutions, thus paving the way for biological applications, and were characterized by several spectroscopic, microscopic, thermogravimetric, and rheological techniques. In vitro experiments demonstrated excellent cytocompatibility.

Indexed as

biomaterialscarbon nanomaterialscarbon nano-onionsD-amino acidsgelshydrogelationnanocompositespeptidesself-assemblysupramolecular chemistry

Identifiers

PMID36616081
PMCPMC9824889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.