Evidence map›Paper›PMID 36615974›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Mitigation of Cellular and Bacterial Adhesion on Laser Modified Poly (2-Methacryloyloxyethyl Phosphorylcholine)/Polydimethylsiloxane Surface.

Simona Nistorescu, Madalina Icriverzi, Paula Florian, Anca Bonciu, Valentina Marascu, Nicoleta Dumitrescu, Gratiela Gradisteanu Pircalabioru, Laurentiu Rusen, Alexandra Mocanu, Anca Roseanu and 4 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Simona NistorescuNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.
Madalina IcriverziInstitute for Biochemistry of Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0003-0282-1825
Paula FlorianInstitute for Biochemistry of Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0002-3322-5682
Anca BonciuNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0001-8508-0916
Valentina MarascuNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0002-5170-1398
Nicoleta DumitrescuNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0002-6180-7073
Gratiela Gradisteanu PircalabioruResearch Institute of the University of Bucharest, 050095 Bucharest, Romania.
Laurentiu RusenNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0002-5689-8038
Alexandra MocanuFaculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-0469-9974
Anca RoseanuInstitute for Biochemistry of Romanian Academy, 060031 Bucharest, Romania.
Anisoara CimpeanFaculty of Biology, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0002-5833-3110
Florin GramaSurgical Department, "Carol Davila" University of Medicine and Pharmacy, 030171 Bucharest, Romania.
Valentina DincaNational Institute for Laser, Plasma and Radiation Physics, 077125 Magurele, Romania.ORCID 0000-0002-3641-5342
Daniel A CristianSurgical Department, "Carol Davila" University of Medicine and Pharmacy, 030171 Bucharest, Romania.ORCID 0000-0003-1798-853X

Funding

Romanian Ministry of Education and Research project number project PN-III-P4-ID-PCE-2020-2375Structural and Functional Proteomics Research Program of the Institute of Biochemistry of the Romanian Academy Project no. 5
6 · The paper itself

Abstract

Nowadays, using polymers with specific characteristics to coat the surface of a device to prevent undesired biological responses can represent an optimal strategy for developing new and more efficient implants for biomedical applications. Among them, zwitterionic phosphorylcholine-based polymers are of interest due to their properties to resist cell and bacterial adhesion. In this work, the Matrix-Assisted Laser Evaporation (MAPLE) technique was investigated as a new approach for functionalising Polydimethylsiloxane (PDMS) surfaces with zwitterionic poly(2-Methacryloyloxyethyl-Phosphorylcholine) (pMPC) polymer. Evaluation of the physical-chemical properties of the new coatings revealed that the technique proposed has the advantage of achieving uniform and homogeneous stable moderate hydrophilic pMPC thin layers onto hydrophobic PDMS without any pre-treatment, therefore avoiding the major disadvantage of hydrophobicity recovery. The capacity of modified PDMS surfaces to reduce bacterial adhesion and biofilm formation was tested for Gram-positive bacteria,

Indexed as

cellular responseMAPLEzwitterionic coating

Identifiers

PMID36615974
PMCPMC9824587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.