Evidence map›Paper›PMID 36615930›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Development of New Health Risk Assessment of Nanoparticles: EPA Health Risk Assessment Revised.

Michal Macko, Jan Antoš, František Božek, Jiří Konečný, Jiří Huzlík, Jitka Hegrová, Ivo Kuřitka

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Michal MackoCentre of Polymer Systems, Tomas Bata University in Zlin, třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic.ORCID 0000-0002-8282-8375
Jan AntošCentre of Polymer Systems, Tomas Bata University in Zlin, třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic.ORCID 0000-0002-7769-8713
František BožekFaculty of Logistics and Crisis Management, Tomas Bata University in Zlin, Studentské nám. 1532, 686 01 Uherské Hradiště, Czech Republic.
Jiří KonečnýFaculty of Logistics and Crisis Management, Tomas Bata University in Zlin, Studentské nám. 1532, 686 01 Uherské Hradiště, Czech Republic.
Jiří HuzlíkTransport Research Centre, Division of Sustainable Transport and Transport Structures Diagnostics, Líšeňská 33a, 619 00 Brno, Czech Republic.ORCID 0000-0003-1912-4831
Jitka HegrováTransport Research Centre, Division of Sustainable Transport and Transport Structures Diagnostics, Líšeňská 33a, 619 00 Brno, Czech Republic.ORCID 0000-0003-1717-6187
Ivo KuřitkaCentre of Polymer Systems, Tomas Bata University in Zlin, třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic.ORCID 0000-0002-1016-5170
Tomas Bata University in Zlín · CZTransport Research Centre · CZ

Funding

Ministry of Education Youth and Sports RP/CPS/2022/007Tomas Bata University in Zlín IGA/CPS/2019/007Tomas Bata University in Zlín IGA/CPS/2020/003Tomas Bata University in Zlín IGA/CPS/2021/002Tomas Bata University in Zlín IGA/CPS/2022/002
6 · The paper itself

Abstract

The concentration of nanoparticles in the ambient air can lead to induced toxicities; however, it appears that nanoparticles’ unique properties are completely omitted when assessing health risks. This paper aims to enhance the EPA health risk assessment by incorporating two new variables that consider the size of nanoparticles: the toxicity multiplier and the size multiplier. The former considers the qualitative aspect of the size of particles within a concentration, whilst the latter takes into account the effects associated with the number of particles of the specific i-th size distribution interval. To observe the impact of the new variables, a case study was performed. The studied element was cadmium, which was measured using ICP-MS to discover concentrations of size fractions, ranging from <15.1 to <9830 nm. Next, the cadmium concentration is assessed using both the current state-of-the-art method and the proposed method with adjustments. Based on the new approach, the final risk was 1.1 × 10−5, which was almost 24 times higher compared with the current method. The contribution of nanoparticles to the risk value grew from barely 6% to an alarming 88%. Therefore, the enhanced method can lead to more realistic results when assessing the health risks of nanoparticles.

Indexed as

health risk assessmentnanoparticlestoxicity

Identifiers

PMID36615930
PMCPMC9823543
OpenAlexW4312041760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.