Evidence map›Paper›PMID 36615565›Full record

Trial reportMolecules (Basel, Switzerland)2023

Single or Daily Application of Topical Curcumin Prevents Ultraviolet B-Induced Apoptosis in Mice.

Khairuddin Djawad, Ilham Jaya Patellongi, Upik Anderiani Miskad, Muhammad Nasrum Massi, Irawan Yusuf, Muhammad Faruk

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Curcumin in High Doses Reverses the UV-B-InducedPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Khairuddin DjawadDepartment of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.ORCID 0000-0002-4569-6385
Ilham Jaya PatellongiDepartment of Physiology, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.
Upik Anderiani MiskadDepartment of Pathological Anatomy, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.
Muhammad Nasrum MassiDepartment of Microbiology, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.
Irawan YusufDepartment of Physiology, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.
Muhammad FarukDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar 90245, Indonesia.ORCID 0000-0002-7079-4585
Hasanuddin University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin is a natural ingredient with antioxidant effects, widely studied as a treatment for various types of cancer. However, its effects on ultraviolet radiation have not been fully explored. The effects of single or daily application of 0.1-100 μM curcumin on cell apoptosis in ultraviolet B (UVB)-induced mice were tested using an experimental double-blind posttest design with a control group and two research models: a single application of curcumin before a single UVB exposure and daily application of curcumin for 7 days before a single UVB exposure on the seventh day. Apoptotic cells were counted using a tunnel system kit. The number of apoptotic cells under a single or daily application of curcumin for 7 days was significantly lower than that of the UVB controls (

Indexed as

CurcuminSkin NeoplasmsAnimalsAntioxidantsApoptosisCyclooxygenase InhibitorsHumansMiceSkinUltraviolet RaysAntioxidantsCurcuminCyclooxygenase Inhibitorsapoptosiscurcuminradiation

Identifiers

PMID36615565
PMCPMC9824043
OpenAlexW4313473085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.