Evidence map›Paper›PMID 36615463›Full record

ReviewMolecules (Basel, Switzerland)2022

Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine.

Zhenyu Zhou, Yingxuan Yan, Hongli Li, Yaru Feng, Cheng Huang, Shengjie Fan

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Nomilin Rewires mTOR-Driven Immunometabolism via DDIT4 to Restrain Psoriasis.International journal of biological sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Insights into the Mechanism of Action of the Degraded Limonoid Prieurianin.International journal of molecular sciences · 2024
    Review
  7. Chemometric discrimination of eightCurrent research in food science · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhenyu ZhouSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yingxuan YanSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hongli LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yaru FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Cheng HuangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Shengjie FanSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID 0000-0002-0184-5641
Shanghai University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81873058National Natural Science Foundation of China 82073951the Fok Ying Tung Education Foundation 171036
6 · The paper itself

Abstract

Nomilin is one of the major limonoids, which are plant secondary metabolites also known as tetranortriterpenoids. Nomilin is found mostly in common edible citrus fruits including lemons, limes, oranges, grapefruits, mandarins, along with traditional Chinese medicines derived from citrus fruits, such as tangerine seed, tangerine peel, fructus aurantii immaturus, etc. A number of studies have demonstrated that nomilin and its analogues exhibit a variety of biological and pharmacological activities. These include anti-cancer, immune-modulatory, anti-inflammatory, anti-obesity, anti-viral, anti-osteoclastogenic, anti-oxidant, and neuro-protective effects. Thus, nomilin and its analogues have emerged as a potential therapy for human diseases. The purpose of this review is to chronicle the evolution of nomilin research from examining its history, structure, occurrence, to its pharmacological and disease-preventing properties as well as its potential utilization in medicine and food science.

Indexed as

BenzoxepinsCitrusLimoninsFruitHumansBenzoxepinsLimoninsnomilinbiological activitiescitrus fruitshealth promotionnomilintetranortriterpenoid

Identifiers

PMID36615463
PMCPMC9822165
OpenAlexW4313327062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.