Evidence map›Paper›PMID 36615412›Full record

ArticleMolecules (Basel, Switzerland)2022

Metabolomic Strategy to Characterize the Profile of Secondary Metabolites in

Xuan Shi, Yu Sun, Junhui Liu, Wencai Liu, Yan Xing, Zhilong Xiu, Yuesheng Dong

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Epigenetic Regulation of Fungal Secondary Metabolism.Journal of fungi (Basel, Switzerland) · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuan ShiSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.
Yu SunSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.
Junhui LiuSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.
Wencai LiuShandong Provincial Engineering Laboratory of Protein Pharmaceutical, Shandong New Time Pharmaceutical Co., Ltd., Linyi 273400, China.
Yan XingSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0002-9659-3079
Zhilong XiuSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.
Yuesheng DongSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-5010-6426

Funding

Fundamental Research Funds for the Central Universities DUT21ZD208Fundamental Research Funds for the Central Universities DUT22YG129Fundamental Research Funds for the Central Universities DUT22YG203
6 · The paper itself

Abstract

Chemical epigenetic regulation (CER) is an effective method to activate the silent pathway of fungal secondary metabolite synthesis. However, conventional methods for CER study are laborious and time-consuming. In the meantime, the overall profile of the secondary metabolites in the fungi treated by the CER reagent is not well characterized. In this study, suberohydroxamic acid (SBHA), a histone deacetylase inhibitor, was added to a culture of

Indexed as

Epigenesis, GeneticTandem Mass SpectrometryAspergillusChromatography, LiquidSecondary MetabolismAspergillus aculeatuschemical epigenetic regulation (CER)secondary metabolites

Identifiers

PMID36615412
PMCPMC9821969

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.