Evidence map›Paper›PMID 36615352›Full record

ReviewMolecules (Basel, Switzerland)2022

Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases-A Review.

Ján Kováč, Lívia Slobodníková, Eva Trajčíková, Katarína Rendeková, Pavel Mučaji, Alice Sychrová, Silvia Bittner Fialová

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Dentistry journal · 2026
    Review
  3. Article
  4. Article
  5. Biosynthesis of Silver Nanoparticles fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Identification of OneInternational journal of molecular sciences · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ján KováčDepartment of Stomatology and Maxillofacial Surgery, Faculty of Medicine, Comenius University in Bratislava, Heydukova 10, 812 50 Bratislava, Slovakia.
Lívia SlobodníkováInstitute of Microbiology, Faculty of Medicine and the University Hospital in Bratislava, Comenius University in Bratislava, Sasinkova 4, 811 08 Bratislava, Slovakia.
Eva TrajčíkováDepartment of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.
Katarína RendekováDepartment of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.
Pavel MučajiDepartment of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.ORCID 0000-0003-4490-2615
Alice SychrováDepartment of Natural Drugs, Faculty of Pharmacy, Masaryk University, Palackého 1946/1, 612 00 Brno, Czech Republic.ORCID 0000-0003-3948-6581
Silvia Bittner FialováDepartment of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.ORCID 0000-0002-7964-8613
Comenius University Bratislava · SKMasaryk University · CZVysoká Škola Zdravotníctva a Sociálnej Práce sv. Alžbety · SK

Funding

Operational Programme Integrated Infrastructure ITMS: 313011T431Slovak Research and Development Agency APVV-19-0056THE MINISTRY OF EDUCATION, SCIENCE, RESEARCH, AND SPORT OF SLOVAKIA - VEGA VEGA 1/0226/22THE MINISTRY OF EDUCATION, SCIENCE, RESEARCH, AND SPORT OF SLOVAKIA - VEGA VEGA 1/0284/20
6 · The paper itself

Abstract

Medicinal plants are rich sources of valuable molecules with various profitable biological effects, including antimicrobial activity. The advantages of herbal products are their effectiveness, relative safety based on research or extended traditional use, and accessibility without prescription. Extensive and irrational usage of antibiotics since their discovery in 1928 has led to the increasing expiration of their effectiveness due to antibacterial resistance. Now, medical research is facing a big and challenging mission to find effective and safe antimicrobial therapies to replace inactive drugs. Over the years, one of the research fields that remained the most available is the area of natural products: medicinal plants and their metabolites, which could serve as active substances to fight against microbes or be considered as models in drug design. This review presents selected flavonoids (such as apigenin, quercetin, kaempferol, kurarinone, and morin) and tannins (including oligomeric proanthocyanidins, gallotannins, ellagitannins, catechins, and epigallocatechin gallate), but also medicinal plants rich in these compounds as potential therapeutic agents in oral infectious diseases based on traditional usages such as

Indexed as

Anti-Infective AgentsCommunicable DiseasesPlants, MedicinalFlavonoidsHydrolyzable TanninsPlant ExtractsTanninsAnti-Infective AgentsFlavonoidsHydrolyzable TanninsPlant ExtractsTanninsantibiofilm activityantimicrobial activityflavonoidsmedicinal plantsnatural productsoral infectionsoral pathogenstannins

Identifiers

PMID36615352
PMCPMC9821998
OpenAlexW4313259718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.