Evidence map›Paper›PMID 36615338›Full record

ArticleMolecules (Basel, Switzerland)2022

Efficacy and Mechanism of Quercetin in the Treatment of Experimental Colitis Using Network Pharmacology Analysis.

Qilian Zhang, Feifei Wen, Fang Sun, Zhengguang Xu, Yanzhan Liu, Chunxue Tao, Fei Sun, Mingchao Jiang, Mingtao Yang, Jing Yao

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  5. Ulceroprotective Effects ofCurrent issues in molecular biology · 2025
    Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qilian ZhangSchool of Basic Medicine, Weifang Medical University, Weifang 261000, China.
Feifei WenSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Fang SunSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Zhengguang XuSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Yanzhan LiuSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Chunxue TaoSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Fei SunSchool of Clinical Medicine, Qilu Medical University, Zibo 255000, China.
Mingchao JiangSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Mingtao YangSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Jing YaoSchool of Basic Medicine, Jining Medical University, Jining 272000, China.
Jining Medical University · CNWeifang Medical University · CN

Funding

National Natural Science Foundation of China No. 81603143Research Fund for Lin He's Academician Workstation of New Medicine and Clinical Translation in Jining Medical University Nos: JYHL2021MS30; JYHL2021FMS13Shandong Traditional Chinese Medicine Science and Technology Project No. 2020Q060; M-2022247
6 · The paper itself

Abstract

Quercetin, a flavonoid that is present in vegetables and fruits, has been found to have anti-inflammatory effects. However, the mechanism by which it inhibits colitis is uncertain. This study aimed to explore the effect and pharmacological mechanism of quercetin on dextran sodium sulfate (DSS)-induced ulcerative colitis (UC). Mice were given a 4% (

Indexed as

ColitisColitis, UlcerativeAnimalsAnti-Inflammatory AgentsColonDextran SulfateDisease Models, AnimalMiceMice, Inbred C57BLNetwork PharmacologyPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktQuercetinAnti-Inflammatory AgentsDextran SulfatePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktQuercetinmolecular docking analysisnetwork pharmacologyPI3K/AKT signalingquercetinulcerative colitis

Identifiers

PMID36615338
PMCPMC9822290
OpenAlexW4313244299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.