Evidence map›Paper›PMID 36615334›Full record

ArticleMolecules (Basel, Switzerland)2022

Biological Activity and Chemical Composition of Propolis from Various Regions of Poland.

Magdalena Woźniak, Anna Sip, Lucyna Mrówczyńska, Justyna Broniarczyk, Agnieszka Waśkiewicz, Izabela Ratajczak

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antiviral and Anticancer Activities of Stingless Bee Propolis fromInternational journal of molecular sciences · 2026
    Article
  6. ComparativeMagnetic resonance in chemistry : MRC · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Bee products as alternatives in the treatment of viral infections.Journal of the science of food and agriculture · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Magdalena WoźniakDepartment of Chemistry, Faculty of Forestry and Wood Technology, Poznan University of Life Sciences, Wojska Polskiego 75, 60625 Poznań, Poland.ORCID 0000-0002-1863-5122
Anna SipDepartment of Biotechnology and Food Microbiology, Faculty of Food Science and Nutrition, Poznan University of Life Sciences, Wojska Polskiego 48, 60627 Poznań, Poland.ORCID 0000-0002-0120-2734
Lucyna MrówczyńskaDepartment of Cell Biology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, 61614 Poznań, Poland.ORCID 0000-0002-4425-5596
Justyna BroniarczykDepartment of Molecular Virology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, 61614 Poznań, Poland.
Agnieszka WaśkiewiczDepartment of Chemistry, Faculty of Forestry and Wood Technology, Poznan University of Life Sciences, Wojska Polskiego 75, 60625 Poznań, Poland.
Izabela RatajczakDepartment of Chemistry, Faculty of Forestry and Wood Technology, Poznan University of Life Sciences, Wojska Polskiego 75, 60625 Poznań, Poland.ORCID 0000-0003-3026-5192
University of Life Sciences in Poznań · PLAdam Mickiewicz University in Poznań · PL

Funding

National Science Centre in Poland 2019/03/X/NZ9/01800
6 · The paper itself

Abstract

Propolis is one of the bee products, with multiple biological properties used in numerous applications. The research objective was to determine the chemical composition and biological properties (antibacterial, antifungal, antiviral, antioxidant, and cytoprotective activity) of propolis extracts collected from various regions of Poland. The results indicated that the total content of phenols (116.16-219.41 mg GAE/g EEP) and flavonoids (29.63-106.07 mg QE/g EEP) in propolis extracts depended on their geographic origin. The high content of epicatechin, catechin, pinobanksin, myricetin, and acids: vanillic and syringic in propolis samples was confirmed by chromatographic analysis. Moreover, the presence of caffeic acid phenethyl ester was confirmed in all samples. The origin of propolis also influenced the biological properties of its extracts. The propolis extracts were characterized by moderate DPPH free radical scavenging activity (29.22-35.14%), and relatively low ferrous iron chelating activity (9.33-32.32%). The results indicated also that the propolis extracts showed high activity in the protection of human red blood cells against free radicals generated from 2,2'-azobis(2-methylpropionamidine) dihydrochloride (AAPH). The extracts exhibited diversified activity against the tested pathogenic bacteria and limited activity against fungal strains. The research of selected propolis extracts showed that only 2 of 5 examined samples showed moderate activity against HPV (human papillomaviruses) and the activity depended on its geographical distribution.

Indexed as

CatechinPropolisAnti-Bacterial AgentsAntioxidantsFlavonoidsHumansPhenolsPolandAnti-Bacterial AgentsAntioxidantsCatechinFlavonoidsPhenolsPropolisantimicrobial activityantioxidant propertiesantiviral activitycytoprotective activityphenolic compoundspropolis

Identifiers

PMID36615334
PMCPMC9822435
OpenAlexW4313259903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.