Evidence map›Paper›PMID 36615326›Full record

ReviewMolecules (Basel, Switzerland)2022

Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies.

Yun-Lei Dai, Ying Li, Qi Wang, Feng-Jv Niu, Kun-Wei Li, Yun-Yu Wang, Jian Wang, Chang-Zheng Zhou, Li-Na Gao

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Review
  8. Green-synthesizedRSC advances · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Unlocking the Secrets of Roman Chamomile (Molecules (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Biogenic silver nanoparticles from chamomile incorporated in hydrogels for high transparent non-infectiveness contact lenses.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yun-Lei DaiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Ying LiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Qi WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Feng-Jv NiuCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Kun-Wei LiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Yun-Yu WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Jian WangCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Chang-Zheng ZhouCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Li-Na GaoCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matricaria chamomilla L. (MC) and Chamaemelum nobile (L.) All. (CN) are two varieties of Chamomile. These herbs have been used for thousands of years in Greece, Rome and ancient Egypt. Chamomile has been used for the treatment of stomach problems, cramps, dermatitis, and minor infections. The purpose of this study was to introduce the botanical characteristics and geographical distribution, traditional uses, chemical constituents, pharmacological activities, toxicity studies and quality control studies, and lay a theoretical foundation for the rational development and utilization of chamomile. This review powered that chemical constituents include flavonoids, coumarins, volatile oils, terpenes, organic acids, polysaccharides, and others. These compounds possess anticancer, anti-infective, anti-inflammatory, antithrombotic, antioxidant, hypolipidaemic, hypoglycaemic, antihypertensive, antidepressant, neuroprotective activities, among others. Chamomile is a widely used herb in traditional medicine. It brings great economic value due to its numerous pharmacological effects and traditional uses. However, more toxicity tests should be carried out to confirm its safety. There is need for further research to provide concrete scientific evidence and validate its medicinal properties.

Indexed as

ChamomileOils, VolatileMedicine, TraditionalPlant ExtractsQuality ControlTerpenesOils, VolatilePlant ExtractsTerpenesChamaemelum nobile (L.) all.chamomilechemical constituentsMatricaria chamomilia L.pharmacological activities

Identifiers

PMID36615326
PMCPMC9822300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.