Evidence map›Paper›PMID 36615270›Full record

ArticleMolecules (Basel, Switzerland)2022

Use of Piranha Solution as An Alternative Route to Promote Bioactivation of PEEK Surface with Low Functionalization Times.

Flavia Suzany Ferreira Dos Santos, José Filipe Bacalhau Rodrigues, Milena Costa da Silva, Maria Eduarda Vasconcelos Barreto, Henrique Nunes da Silva, Suédina Maria de Lima Silva, Marcus Vinicius Lia Fook

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Flavia Suzany Ferreira Dos SantosDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.ORCID 0000-0002-9481-2231
José Filipe Bacalhau RodriguesDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.ORCID 0000-0002-3916-6214
Milena Costa da SilvaDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.
Maria Eduarda Vasconcelos BarretoDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.ORCID 0000-0003-2319-7371
Henrique Nunes da SilvaDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.ORCID 0000-0002-1947-0075
Suédina Maria de Lima SilvaDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.ORCID 0000-0002-2073-0989
Marcus Vinicius Lia FookDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande, PB 58429-900, Brazil.

Funding

Fundação para a Ciência e Tecnologia 88882.455347/2019-01
6 · The paper itself

Abstract

This study aimed to achieve bioactivity on the PEEK surface using piranha solution through a lower functionalization time. For this purpose, the functionalization occurred with piranha solution and 98% sulfuric acid in the proportions of 1:2, 1:1, and 2:1 at periods of 30, 60, and 90 s. The samples treated for longer times at higher concentrations registered the characteristic spectroscopy band associated with sulfonation. Additionally, both chemical treatments allowed the opening of the aromatic ring, increasing the number of functional groups available and making the surface more hydrophilic. The piranha solution treatments with higher concentrations and longer times promoted greater heterogeneity in the surface pores, which affected the roughness of untreated PEEK. Furthermore, the treatments induced calcium deposition on the surface during immersion in SBF fluid. In conclusion, the proposed chemical modifications using sulfuric acid SPEEK 90 and, especially, the piranha solution PEEK-PS 2:1-90, were demonstrated to be promising in promoting the rapid bioactivation of PEEK-based implants.

Indexed as

KetonesPolyethylene GlycolsBenzophenonesPolymersSulfuric AcidsSurface PropertiesBenzophenonesKetonespolyetheretherketonePolyethylene GlycolsPolymerssulfuric acidSulfuric AcidsPEEKpiranha solutionsulfonic acid functional groupsulfuric acidsurface bioactivation

Identifiers

PMID36615270
PMCPMC9822504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.