Electroanalysis of Ibuprofen and Its Interaction with Bovine Serum Albumin.

Muhammad Dilshad, Afzal Shah, Shamsa Munir

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.5field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Muhammad DilshadDepartment of Chemistry, Quaid-Azam University, Islamabad 45320, Pakistan.

Afzal ShahDepartment of Chemistry, Quaid-Azam University, Islamabad 45320, Pakistan.ORCID 0000-0002-9465-9185

Shamsa MunirSchool of Applied Sciences and Humanities, National University of Technology (NUTECH), Islamabad 44000, Pakistan.ORCID 0000-0003-2483-5179

Quaid-i-Azam University · PKNational University of Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current work presents a sensitive, selective, cost-effective, and environmentally benign protocol for the detection of ibuprofen (IBP) by an electrochemical probe made of a glassy carbon electrode modified with Ag-ZnO and MWCNTs. Under optimized conditions, the designed sensing platform was found to sense IBP up to a 28 nM limit of detection. The interaction of IBP with bovine serum albumin (BSA) was investigated by differential pulse voltammetry. IBP-BSA binding parameters such as the binding constant and the stoichiometry of complexation were calculated. The results revealed that IBP and BSA form a single strong complex with a binding constant value of 8.7 × 10

Indexed as

IbuprofenSerum Albumin, BovineCarbonElectrochemical TechniquesElectrodesProtein BindingCarbonIbuprofenSerum Albumin, Bovinebovine serum albuminibuprofeninflammationmodified glassy carbon

Identifiers

PMID36615246

DOI10.3390/molecules28010049

PMCPMC9821973

OpenAlexW4313470133

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.