Evidence map›Paper›PMID 36615224›Full record

ArticleMolecules (Basel, Switzerland)2022

The Antimicrobial and Toxicity Influence of Six Carrier Oils on Essential Oil Compounds.

Salehah Moola, Ané Orchard, Sandy van Vuuren

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Larvicidal Activities ofPlants (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Frontiers in pharmacology · 2024
    Review
  6. New Weapons to Fight againstAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Salehah MoolaDepartment of Pharmacy and Pharmacology, Therapeutic Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.
Ané OrchardDepartment of Pharmacy and Pharmacology, Therapeutic Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.
Sandy van VuurenDepartment of Pharmacy and Pharmacology, Therapeutic Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0002-4859-1845
University of the Witwatersrand · ZA

Funding

National Research Foundation 129672
6 · The paper itself

Abstract

Essential oil compounds have been identified as alternative antimicrobials; however, their use is limited due to their toxicity on human lymphocytes, skin, and reproduction. Carrier oils can reduce the toxicity of essential oils, which raises the question as to whether such activity would extend to the essential oil compounds. Thus, this study aimed to investigate the antimicrobial and toxicity activity of essential oil compounds in combination with carrier oils. The antimicrobial properties of the essential oil compounds, alone and in combination with carrier oils, were determined using the broth microdilution assay. The toxicity was determined using the brine shrimp lethality assay. Antimicrobial synergy (ΣFIC ≤ 0.50) occurred in 3% of the samples when tested against the ESKAPE pathogens. The compound thymoquinone in combination with the carrier oil

Indexed as

Anti-Infective AgentsOils, VolatileHumansMicrobial Sensitivity TestsPlant OilsSkinAnti-Infective AgentsOils, VolatilePlant OilsantimicrobialCalendula officinaliscarrier oilsESKAPEessential oil compoundminimum inhibitory concentrationpercentage mortalityPrunus armeniacaselectivity indexthymoquinonetoxicity

Identifiers

PMID36615224
PMCPMC9821837
OpenAlexW4313467554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.