Evidence map›Paper›PMID 36615218›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer's Disease Candidates: Evidence-Based In Vitro Study.

Fazal Rahim, Hayat Ullah, Muhammad Taha, Rafaqat Hussain, Maliha Sarfraz, Rashid Iqbal, Naveed Iqbal, Shoaib Khan, Syed Adnan Ali Shah, Marzough Aziz Albalawi and 7 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Fazal RahimDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Hayat UllahDepartment of Chemistry, University of Okara, Okara 56130, Pakistan.ORCID 0000-0003-3833-1457
Muhammad TahaDepartment of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.ORCID 0000-0003-3047-9289
Rafaqat HussainDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Maliha SarfrazDepartment of Zoology, Wildlife and Fisheries, Sub-Campus Toba Tek Singh, University of Agriculture Faisalabad, Punjab 36050, Pakistan.
Rashid IqbalDepartment of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.ORCID 0000-0003-0473-889X
Naveed IqbalDepartment of Chemistry, University of Poonch, Rawalakot 12350, Pakistan.
Shoaib KhanDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.ORCID 0000-0001-5404-0954
Syed Adnan Ali ShahFaculty of Pharmacy, Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam 42300, Selangor, Malaysia.ORCID 0000-0002-8142-5013
Marzough Aziz AlbalawiDepartment of Chemistry, Alwajh College, University of Tabuk, Tabuk 47512, Saudi Arabia.ORCID 0000-0003-4579-0045
Mahmoud A AbdelazizDepartment of Chemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-1317-0653
Fatema Suliman AlatawiDepartment of Biochemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-3595-7828
Abdulrahman AlasmariDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.
Mohamed I SakranDepartment of Biochemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0003-2295-6874
Nahla ZidanDepartment of Nutrition and Food Science, Faculty of Home Economics, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-7187-6419
Ibrahim JafriDepartment of Biotechnology, Faculty of Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0002-8465-6829
Khalid Mohammed KhanH.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triazole-based thiosemicarbazone derivatives (

Indexed as

Alzheimer DiseaseCholinesterase InhibitorsThiosemicarbazonesAcetylcholinesteraseButyrylcholinesteraseHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAcetylcholinesteraseButyrylcholinesteraseCholinesterase InhibitorsThiosemicarbazonesacetylcholinesterasebutyrylcholinesterasemolecular docking studystructure activity relationshipthiosemicarbazonetriazole

Identifiers

PMID36615218
PMCPMC9821906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.