Evidence map›Paper›PMID 36615213›Full record

ArticleMolecules (Basel, Switzerland)2022

Neobaicalein Inhibits Th17 Cell Differentiation Resulting in Recovery of Th17/Treg Ratio through Blocking STAT3 Signaling Activation.

Jian-Yu Chen, Ying-Jie Yang, Xue-Qin Ma, Qi Cao, Shan-Shan Wei, Rong-Rong Pan, Li-Hong Nan, Yao-Jun Liu, Yan Cao, Xiao-Yun Tian and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Jian-Yu ChenDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.ORCID 0000-0003-2578-6524
Ying-Jie YangDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Xue-Qin MaKey Laboratory of Hui Ethnic Medicine Modernization, Department of Pharmaceutical Analysis, School of Pharmacy, Ministry of Education, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China.ORCID 0000-0003-4818-5967
Qi CaoSchool of Pharmacy, Second Military Medical University, No. 325, Guo He Road, Shanghai 200433, China.
Shan-Shan WeiSchool of Pharmacy, Second Military Medical University, No. 325, Guo He Road, Shanghai 200433, China.
Rong-Rong PanSeventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No. 358, Datong Road, Pudong New Area, Shanghai 200137, China.
Li-Hong NanDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Yao-Jun LiuDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Yan CaoSchool of Pharmacy, Second Military Medical University, No. 325, Guo He Road, Shanghai 200433, China.
Xiao-Yun TianDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Shan DengDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Zai-Xing ChengDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Can-Jian WangNational Engineering Research Center of Chinese Medicine Solid Preparation Manufacturing Technology, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Tao ChenDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.
Yan-Fang ZhengDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.ORCID 0000-0003-4731-4499
Ming-Qing HuangDepartment of Pharmacology, School of Pharmacy, Fujian University of Traditional Chinese Medicine, No. 1, Hua Tuo Road, Min Hou Shang Jie, Fuzhou 350122, China.ORCID 0000-0002-2853-1087
Fujian University of Traditional Chinese Medicine · CNSecond Military Medical University · CNJiangxi University of Traditional Chinese Medicine · CNNingxia Medical University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

Collaborative Innovation Platform Project of Fuxiaquan National Innovation Demonstration Zone 2021FX02Foundation of Fujian University of Traditional Chinese Medicine No. X2019004Fujian Provincial Marine Economic Development Special Fund Project FJHJF-L-2021-4National Natural Science Foundation of China No. 81903629Natural Science Foundation of Fujian Province 2022J01868The National Natural Science Foundation of China 81973437
6 · The paper itself

Abstract

Huangqin is the dried root of

Indexed as

Autoimmune DiseasesTh17 CellsCell DifferentiationHumansSignal TransductionSTAT3 Transcription FactorSTAT5 Transcription FactorT-Lymphocytes, RegulatorySTAT3 protein, humanSTAT3 Transcription FactorSTAT5 Transcription Factoractivators of transcription 3 (STAT3)autoimmune diseasesneobaicalein (NEO)signal transducerTh17

Identifiers

PMID36615213
PMCPMC9822447
OpenAlexW4312039562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.