Evidence map›Paper›PMID 36615169›Full record

ArticleJournal of clinical medicine2023

Effect of Exercise Interventions on Irisin and Interleukin-6 Concentrations and Indicators of Carbohydrate Metabolism in Males with Metabolic Syndrome.

Karol Makiel, Agnieszka Suder, Aneta Targosz, Marcin Maciejczyk, Alon Haim

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Observational
  7. Review
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  12. Review
  13. Review
  14. Therapeutic Potential of Irisin in Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Karol MakielDepartment of Anatomy, Faculty of Physical Rehabilitation, University of Physical Education, 31-571 Cracow, Poland.
Agnieszka SuderDepartment of Anatomy, Faculty of Physical Rehabilitation, University of Physical Education, 31-571 Cracow, Poland.ORCID 0000-0001-6135-8274
Aneta TargoszDepartment of Physiology, Faculty of Medicine, Jagiellonian University Medical College, 31-531 Cracow, Poland.
Marcin MaciejczykDepartment of Physiology and Biochemistry, Faculty of Physical Education and Sport, University of Physical Education, 31-571 Cracow, Poland.ORCID 0000-0002-9505-4081
Alon HaimDepartment of Endocrinology and Diabetes, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 653, Israel.ORCID 0000-0002-0649-2603
Ben-Gurion University of the Negev · ILJagiellonian University · PL

Funding

The research project has been financed within the program of the Ministry of Science and Higher Education in Poland 'Regional Initiative of Excellence' in the years 2019-2022 Project No. 022/RID/2018/19 in the amount of 11 919 908 PLN
6 · The paper itself

Abstract

Irisin (IR) is a biomarker that is associated with metabolic syndrome (MetS). However, the available evidence on the association of IR, physical activity, and MetS status are contradictory. Therefore, the present study aimed to investigate the effect of exercise intervention on IR and interleukin-6 (IL-6) levels and indicators of carbohydrate metabolism in males with MetS. The study included 62 males with MetS (age 36.6 ± 6.9 years, BMI 33.6 ± 4.4 kg/m

Indexed as

exerciseinterlekin-6irisinmetabolic syndromeobesityphysical activity

Identifiers

PMID36615169
PMCPMC9820823
OpenAlexW4313516301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.