Evidence map›Paper›PMID 36615133›Full record

ReviewJournal of clinical medicine2023

Left Ventricular Adverse Remodeling in Ischemic Heart Disease: Emerging Cardiac Magnetic Resonance Imaging Biomarkers.

Camilla Calvieri, Alessandra Riva, Francesco Sturla, Lorenzo Dominici, Luca Conia, Carlo Gaudio, Fabio Miraldi, Francesco Secchi, Nicola Galea

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A matter of time: Cardiac aneurysm and recurrent thromboembolic events.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
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  5. Observational
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Camilla CalvieriDepartment of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00100 Rome, Italy.
Alessandra RivaDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, 20129 Milan, Italy.ORCID 0000-0001-9648-7711
Francesco SturlaDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, 20129 Milan, Italy.ORCID 0000-0001-7317-304X
Lorenzo DominiciDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0003-2508-4143
Luca ConiaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00100 Rome, Italy.
Carlo GaudioDepartment of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00100 Rome, Italy.
Fabio MiraldiDepartment of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00100 Rome, Italy.
Francesco SecchiUnit of Radiology, IRCCS Policlinico San Donato, 20097 Milan, Italy.
Nicola GaleaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0003-4708-5120
Sapienza University of Rome · ITIRCCS Policlinico San Donato · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-ischemic left ventricular (LV) remodeling is a biologically complex process involving myocardial structure, LV shape, and function, beginning early after myocardial infarction (MI) and lasting until 1 year. Adverse remodeling is a post-MI maladaptive process that has been associated with long-term poor clinical outcomes. Cardiac Magnetic Resonance (CMR) is the best tool to define adverse remodeling because of its ability to accurately measure LV end-diastolic and end-systolic volumes and their variation over time and to characterize the underlying myocardial changes. Therefore, CMR is the gold standard method to assess in vivo myocardial infarction extension and to detect the presence of microvascular obstruction and intramyocardial hemorrhage, both associated with adverse remodeling. In recent times, new CMR quantitative biomarkers emerged as predictive of post-ischemic adverse remodeling, such as T1 mapping, myocardial strain, and 4D flow. Additionally, CMR T1 mapping imaging may depict infarcted tissue and assess diffuse myocardial fibrosis by using surrogate markers such as extracellular volume fraction, which may predict functional recovery or risk stratification of remodeling. Finally, there is emerging evidence supporting the utility of intracavitary blood flow kinetic energy and hemodynamic features assessed by the 4D flow CMR technique as early predictors of remodeling.

Indexed as

4D flowadverse remodelingcardiac magnetic resonance imagingfeature-tracking myocardial strainleft ventricular remodelingmyocardial infarctionsurgical ventricular restoration

Identifiers

PMID36615133
PMCPMC9820966
OpenAlexW4313472798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.