Evidence map›Paper›PMID 36615098›Full record

ArticleJournal of clinical medicine2022

Autism Spectrum Disorder May Be Highly Prevalent in People with Functional Neurological Disorders.

Belén González-Herrero, Francesca Morgante, Javier Pagonabarraga, Biba Stanton, Mark J Edwards

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Belén González-HerreroNeurosciences Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, UK.
Francesca MorganteNeurosciences Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, UK.ORCID 0000-0002-9834-3639
Javier PagonabarragaDepartamento de Medicina, Universidad Autónoma de Barcelona (UAB), 08193 Bellaterra, Spain.ORCID 0000-0002-3248-704X
Biba StantonNeurology Department, King's College Hospital, London SE5 9RS, UK.
Mark J EdwardsDepartment of Clinical and Basic Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Universitat Autònoma de Barcelona · ESKing's College London · GBSouth London and Maudsley NHS Foundation Trust · GBUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent observations suggest that autism spectrum disorder (ASD) co-occurs in people with a functional neurological disorder (FND), but little systematic data are available on the relationship between FND and autism. The study aimed to assess the self-reported autistic traits via a standardized questionnaire and the prevalence of previously diagnosed ASD among people with FND and their 1st-degree relatives. We performed a survey of members of the patient organization FNDHope, using a self-completed questionnaire for screening for autistic traits and ASD: the adult autism subthreshold spectrum (AdAS spectrum). There were 344 respondents diagnosed with FND with a mean age of 39.8 ± 11.6 years (female sex 90%). Eight per cent of respondents volunteered a previous diagnosis of ASD, and 24% reported a 1st-degree relative with a formal diagnosis of ASD, mostly their children. We found that 69% of respondents had scores in the AdAS spectrum indicating a clinically significant ASD and 21% indicating autistic traits. Further studies are needed to provide more evidence regarding the prevalence of ASD in people with FND and how this may influence the aetiology, treatment selection and prognosis.

Indexed as

autism spectrum disorderautistic traitsco-occurrencefunctional neurological disordersprevalence

Identifiers

PMID36615098
PMCPMC9821674
OpenAlexW4313471711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.