ArticleJournal of clinical medicine2022
Effects of Ambient Air Pollution on Precocious Puberty: A Case-Crossover Analysis in Nanjing, China.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Comprehensive clinical outcomes of TiRobot-assisted minimally invasive surgery for pelvic fractures: a meta-analysis.Journal of robotic surgery · 2026Pooled it
- Ambient Air Pollution, Polycyclic Aromatic Hydrocarbons, and Pubertal Development: A Critical Review of Emerging Evidence.Current environmental health reports · 2026Review
- A cross-sectional study of environmental quality and the timing of menarche and menopause in India using national survey and environmental monitoring datasets.Communications medicine · 2026Article
- Pollution burden and trajectories of pubertal development: Implications for sleep disturbances and depressive symptoms.Psychoneuroendocrinology · 2025Article
- Internal Exposure to BTEX in Tropical Children: Does Exposure Speed Up Pubertal Development?Antioxidants (Basel, Switzerland) · 2025Article
- Article
- The trend of suicide and self-harm in the Chinese population from 2018 to 2022 based on ambulance medical emergency cases: a retrospective study.Frontiers in public health · 2025Article
- Exposure to air pollution and precocious puberty: a systematic review.Ewha medical journal · 2024Review
- Long-term exposure to ambient PMBMC public health · 2024Article
- Short-Term Exposure to PMToxics · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAmbient air pollution is closely related to a variety of health outcomes. Few studies have focused on the correlations between air pollution exposure and children's sexual development. In this study, we investigated the potential effects of exposure to air pollution on precocious puberty among children using real-world evidence.
methodsWe conducted a case-crossover study (n = 2201) to investigate the effect of ambient air pollution exposure on precocious puberty from January 2016 to December 2021. Average exposure levels of PM
resultsThe mean age of the children who were diagnosed with precocious puberty was 7.47 ± 1.24 years. The average concentration of PM
conclusionOur findings supported that short-term exposure to air pollution was the risk factor for precocious puberty. Every effort should be made to protect children from air pollution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.