Evidence map›Paper›PMID 36615035›Full record

ArticleJournal of clinical medicine2022

Landscape and Predictive Significance of the Structural Classification of

Linping Gu, Huayan Huang, Zhangwendi Xu, Xiaomin Niu, Ziming Li, Liliang Xia, Yongfeng Yu, Shun Lu

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062823 (An Open-label Phase II Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations Categorized According to Structural Based Classification), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062823 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

An Open-label Phase II Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations Categorized According to Structural Based Classification

TypeinterventionalSponsorNational University Hospital, SingaporeRan2024 to 2026Enrolled35ConditionsNSCLCArmsAfatinib 40 MG
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Linping GuDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Huayan HuangDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Zhangwendi XuDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Xiaomin NiuDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Ziming LiDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Liliang XiaDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Yongfeng YuDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.
Shun LuDepartment of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai 200030, China.ORCID 0000-0001-8833-7262
Shanghai Jiao Tong University · CN

Funding

Beijing CSCO (Sisco) Clinical Oncology Research Grant Y-HS202101-0205Key research project of Collaborative Innovation Center for Biomedical Clinical Research and Transformation from Ministry of Education and Shanghai CCTS-202204National Multi-disciplinary Treatment Project for Major Diseases 2020NMDTPNational Natural Science Foundation of China 82030045Project of Shanghai Talent Development Fund 2019074Projects of the Committee of Shanghai Science and Technology 19ZR1449800 and 20Y11913700The Technology Transfer Project of Shanghai Jiao Tong University School of Medicine No. ZT202010
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EGFR mutationsEGFR TKIsNSCLCstructural classificationtime to treatment failure

Identifiers

PMID36615035
PMCPMC9821726
OpenAlexW4313290027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.