Evidence map›Paper›PMID 36615026›Full record

ReviewJournal of clinical medicine2022

Molecular Diagnosis of Hypertrophic Cardiomyopathy (HCM): In the Heart of Cardiac Disease.

Marilena Melas, Eleftherios T Beltsios, Antonis Adamou, Konstantinos Koumarelas, Kim L McBride

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Identification of recurrentCardiovascular diagnosis and therapy · 2025
    Article
  3. Review
  4. Article
  5. Interplay ofFrontiers in cardiovascular medicine · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. High prevalence ofFrontiers in cardiovascular medicine · 2024
    Article
  16. Review
  17. A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Marilena MelasNew York Genome Center, New York, NY 10013, USA.
Eleftherios T BeltsiosWest Germany Heart Center, Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0001-6193-2109
Antonis AdamouDepartment of Radiology-Medical Imaging, University Hospital Larissa, 41110 Larissa, Greece.ORCID 0000-0003-2524-0302
Konstantinos KoumarelasFaculty of Medicine, School of Health Sciences, University of Thessaly, 41110 Larissa, Greece.
Kim L McBrideCenter for Cardiovascular Research, Nationwide Children's Hospital, and Department of Pediatrics, Ohio State University, Columbus, OH 43205, USA.ORCID 0000-0002-8407-8942
Nationwide Children's Hospital · USNew York Genome Center · USUniversity Hospital of Larissa · GRUniversity of Thessaly · GRWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is an inherited myocardial disease with the presence of left ventricular hypertrophy (LVH). The disease is characterized by high locus, allelic and phenotypic heterogeneity, even among members of the same family. The list of confirmed and potentially relevant genes implicating the disease is constantly increasing, with novel genes frequently reported. Heterozygous alterations in the five main sarcomeric genes (

Indexed as

genetic testinghypertrophic cardiomyopathy (HCM)next generation sequencing

Identifiers

PMID36615026
PMCPMC9821215
OpenAlexW4312226310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.