Evidence map›Paper›PMID 36615005›Full record

ReviewJournal of clinical medicine2022

Long-Term Survival after Extended Sleeve Lobectomy (ESL) for Central Non-Small Cell Lung Cancer (NSCLC): A Meta-Analysis with Reconstructed Time-to-Event Data.

Dimitrios E Magouliotis, Prokopis-Andreas Zotos, Anna P Karamolegkou, Evangelos Tatsios, Kyriakos Spiliopoulos, Thanos Athanasiou

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dimitrios E MagouliotisDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.ORCID 0000-0001-5417-6392
Prokopis-Andreas ZotosDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Anna P KaramolegkouDepartment of Anesthesiology, Hippocration General Hospital of Athens, 41500 Athens, Greece.ORCID 0000-0003-4154-201X
Evangelos TatsiosDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Kyriakos SpiliopoulosDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Thanos AthanasiouDepartment of Surgery and Cancer, Imperial College London, St Mary's Hospital, London W2 1NY, UK.
University of Thessaly · GRHippocration General Hospital · GRSt Mary's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe conducted a thorough literature search on patients with central non-small cell lung cancer (NSCLC) undergoing either extended sleeve lobectomy (ESL) or pneumonectomy (PN).

methodsWe identified all original research studies that compared the long-term survival of ESL versus PN from 1990 to 2022. The primary endpoints were the median overall survival (OS) and disease-free survival (DFS). Complications, operative mortality, and the reoperation rate were the secondary endpoints. Regarding the primary endpoints, independent patient data were extracted from the included studies, and pooled Kaplan-Meier curves were constructed. A sensitivity analysis was performed using the leave-one-out method.

resultsNine studies were included in the qualitative and seven in the quantitative synthesis, including 431 patients. Patients in the ESL group demonstrated a significantly higher OS compared with the PN group (HR, 0.63; 95% CI, 0.46-0.87;

conclusionsThe present meta-analysis indicates that ESL is associated with enhanced survival outcomes compared to PN for patients with central NSCLC. Further randomized controlled trials are necessary to validate our findings.

Indexed as

ESLextended sleeve lobectomylung cancerNSCLCpneumonectomy

Identifiers

PMID36615005
PMCPMC9821210
OpenAlexW4313414272

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.