Evidence map›Paper›PMID 36614970›Full record

ArticleJournal of clinical medicine2022

How to Perform Intravesical Chemotherapy after Second TURBT for Non-Muscle-Invasive Bladder Cancer: A Single-Center Experience.

Zhen Li, Nienie Qi, Zhimin Gao, Li Ding, Jiawei Zhu, Qingxiang Guo, Junqi Wang, Rumin Wen, Hailong Li

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhen LiDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Nienie QiDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Zhimin GaoDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Li DingDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Jiawei ZhuDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Qingxiang GuoDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Junqi WangDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Rumin WenDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Hailong LiDepartment of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Xuzhou Medical College · CN

Funding

Post-doctoral Research Funding Project in Jiangsu Province 2021K447CProject supported by the Natural Science Foundation of the Jiangsu Higher Education Institutions of China 19KJB310001Second Round of Xuzhou Medical Leading Talents Training Project XWRCHT20210027Six talent peaks project in Jiangsu Province WSW-064The Science and Technology Planning Project of Traditional Chinese Medicine of Jiangsu YB2020050
6 · The paper itself

Abstract

purposeThe objective of this study aimed to explore whether the original IVC regimen should be continued after the second TURBT or whether the IVC induction phase should be restarted from the beginning.

methodsA retrospective analysis was performed on 137 patients who underwent a second TURBT at the Affiliated Hospital of Xuzhou Medical University between April 2014 and June 2022. Based on the pathological findings, patients were divided into two groups: group A patients, who did not have a residual tumor on pathological examination after the second TURBT; and group B patients, who had residual tumor. Recurrence was determined using cystoscopy and imaging every three months. The endpoint was recurrence-free survival.

resultIn the entire cohort, there was a statistically significant difference in the RFS between patients in the two IVC regimens (

conclusionIf the pathological findings of the second TURBT specimen is benign, patients can continue their previous treatment regimen without restarting an IVC induction phase. Unnecessary IVC can be avoided in these patients. In contrast, for patients with residual tumors in the second TURBT specimen, the need to restart the IVC induction phase should be emphasized to improve patient prognosis.

Indexed as

chemotherapyresidual tumorsecond-look TURBTurinary bladder neoplasm

Identifiers

PMID36614970
PMCPMC9820835
OpenAlexW4313245904

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.