Evidence map›Paper›PMID 36614892›Full record

ArticleJournal of clinical medicine2022

Clinical Effectiveness of Non-Immersive Virtual Reality Tasks for Post-Stroke Neuro-Rehabilitation of Distal Upper-Extremities: A Case Report.

Debasish Nath, Neha Singh, Megha Saini, Onika Banduni, Nand Kumar, Madakasira Vasantha Padma Srivastava, Shanmugam Senthil Kumaran, Amit Mehndiratta

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Debasish NathCentre for Biomedical Engineering, Indian Institute of Technology Delhi (IITD), New Delhi 110016, India.ORCID 0000-0002-7660-1297
Neha SinghCentre for Biomedical Engineering, Indian Institute of Technology Delhi (IITD), New Delhi 110016, India.
Megha SainiCentre for Biomedical Engineering, Indian Institute of Technology Delhi (IITD), New Delhi 110016, India.ORCID 0000-0002-4416-6737
Onika BanduniCentre for Biomedical Engineering, Indian Institute of Technology Delhi (IITD), New Delhi 110016, India.
Nand KumarDepartment of Psychiatry, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India.
Madakasira Vasantha Padma SrivastavaDepartment of Neurology, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India.
Shanmugam Senthil KumaranDepartment of Nuclear Medicine and Resonance, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India.
Amit MehndirattaCentre for Biomedical Engineering, Indian Institute of Technology Delhi (IITD), New Delhi 110016, India.ORCID 0000-0001-6477-2462
All India Institute of Medical Sciences · INIndian Institute of Technology Delhi · IN

Funding

Indian Council of Medical Research 55/4/1/CARE-Disability & AT/2020/NCD-IIScience and Engineering Research Board TTR/2021/000035
6 · The paper itself

Abstract

A library of non-immersive Virtual Reality (VR) tasks were developed for post-stroke rehabilitation of distal upper extremities. The objective was to evaluate the rehabilitation impact of the developed VR-tasks on a patient with chronic stroke. The study involved a 50-year-old male patient with chronic (13 month) stroke. Twenty VR therapy sessions of 45 min each were given. Clinical scales, cortical-excitability measures, functional MRI (fMRI), and diffusion tensor imaging (DTI) data were acquired pre-and post-therapy to evaluate the motor recovery. Increase in Fugl-Meyer Assessment (wrist/hand) by 2 units, Barthel Index by 5 units, Brunnstrom Stage by 1 unit, Addenbrooke's Cognitive Examination by 3 units, Wrist Active Range of Motion by 5° and decrease in Modified Ashworth Scale by 1 unit were observed. Ipsilesional Motor Evoked Potential (MEP) amplitude (obtained using Transcranial Magnetic Stimulation) was increased by 60.9µV with a decrease in Resting Motor Threshold (RMT) by 7%, and contralesional MEP amplitude was increased by 56.2µV with a decrease in RMT by 7%. The fMRI-derived Laterality Index of Sensorimotor Cortex increased in precentral-gyrus (from 0.28 to 0.33) and in postcentral-gyrus (from 0.07 to 0.3). The DTI-derived FA-asymmetry decreased in precentral-gyrus (from 0.029 to 0.024) and in postcentral-gyrus (from 0.027 to 0.017). Relative reduction in task-specific performance metrics, i.e., time taken to complete the task (31.6%), smoothness of trajectory (76.7%), and relative percentage error (80.7%), were observed from day 1 to day 20 of the VR therapy. VR therapy resulted in improvement in clinical outcomes in a patient with chronic stroke. The research also gives insights to further improve the overall system of rehabilitation.

Indexed as

case reportcortical excitabilitydistal upper extremitiesDTIfMRIneuro-rehabilitationstrokevirtual reality

Identifiers

PMID36614892
PMCPMC9820917
OpenAlexW4312100552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.