ReviewMaterials (Basel, Switzerland)2022
Advances in Multifunctional Bioactive Coatings for Metallic Bone Implants.
Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 89 citations in OpenAlex.
- AI for bioactive materials: From material design to biological applications.Bioactive materials · 2026Review
- Biocompatible Thin Films Deposited by Laser Techniques.Materials (Basel, Switzerland) · 2026Review
- Long-term Performance and Durability of Biomaterials and Implant Designs in Total Joint Arthroplasty and Spinal Fusion.Journal of orthopaedics and sports medicine · 2026Article
- Bioprinting revolution: Innovative design of 3D bioactive scaffolds for living organs and transdermal tissues.Bioengineering & translational medicine · 2025Review
- Advancements in Nanotechnology for Spinal Surgery: Innovations in Spinal Fixation Devices for Enhanced Biomechanical Performance and Osteointegration.Nanomaterials (Basel, Switzerland) · 2025Review
- Research Progress in Medical Biomaterials for Bone Infections.Journal of functional biomaterials · 2025Review
- Fixation Failure in Osteoporotic Bone: A Review of Complications and Outcomes.Indian journal of orthopaedics · 2025Review
- Magnesium-Titanium Alloys: A Promising Solution for Biodegradable Biomedical Implants.Materials (Basel, Switzerland) · 2024Review
- Electrospun PVP Fibers as Carriers of CaMolecules (Basel, Switzerland) · 2024Article
- Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview.International journal of molecular sciences · 2024Review
- Recent Advances in Antibacterial Coatings to Combat Orthopedic Implant-Associated Infections.Molecules (Basel, Switzerland) · 2024Review
- The activity of monocyte-derived macrophages after stimulation with platelet-rich and platelet-poor concentrates. Study on an ovine model of insertion of a tibial implant coated with silicon-doped diamond-like carbon.Journal of veterinary research · 2024Article
- Influence of Thermal Annealing on Mechanical and Optical Property of SiOMaterials (Basel, Switzerland) · 2024Article
- Enhanced bacteriostasis and osseointegrative properties of SiRNA-modified polyetheretherketone surface for implant applications.PloS one · 2024Article
- Fibronectin Conformations after Electrodeposition onto 316L Stainless Steel Substrates Enhanced Early-Stage Osteoblasts' Adhesion but Affected Their Behavior.Journal of functional biomaterials · 2023Article
- Influence of Topography and Composition of Commercial Titanium Dental Implants on Cell Adhesion of Human Gingiva-Derived Mesenchymal Stem Cells: An In Vitro Study.International journal of molecular sciences · 2023Article
- Nanotechnology development in surgical applications: recent trends and developments.European journal of medical research · 2023Review
- Optical Characterization of Materials for Precision Reference Spheres for Use with Structured Light Sensors.Materials (Basel, Switzerland) · 2023Article
- Bioactive coatings for biomedical engineering application: A review of mechanical integrity, biocompatibility, and future smart technologies.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
To fix the bone in orthopedics, it is almost always necessary to use implants. Metals provide the needed physical and mechanical properties for load-bearing applications. Although widely used as biomedical materials for the replacement of hard tissue, metallic implants still confront challenges, among which the foremost is their low biocompatibility. Some of them also suffer from excessive wear, low corrosion resistance, infections and shielding stress. To address these issues, various coatings have been applied to enhance their in vitro and in vivo performance. When merged with the beneficial properties of various bio-ceramic or polymer coatings remarkable bioactive, osteogenic, antibacterial, or biodegradable composite implants can be created. In this review, bioactive and high-performance coatings for metallic bone implants are systematically reviewed and their biocompatibility is discussed. Updates in coating materials and formulations for metallic implants, as well as their production routes, have been provided. The ways of improving the bioactive coating performance by incorporating bioactive moieties such as growth factors, osteogenic factors, immunomodulatory factors, antibiotics, or other drugs that are locally released in a controlled manner have also been addressed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.