Evidence map›Paper›PMID 36614195›Full record

ArticleInternational journal of molecular sciences2023

Snap29 Is Dispensable for Self-Renewal Maintenance but Required for Proper Differentiation of Mouse Embryonic Stem Cells.

Yumei Jia, Zhaoyuan Guo, Jiahao Zhu, Guanyu Qin, Wenwen Sun, Yu Yin, Haiying Wang, Renpeng Guo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yumei JiaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Zhaoyuan GuoCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jiahao ZhuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Guanyu QinCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Wenwen SunCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yu YinYunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, China.
Haiying WangState Key Laboratory of Medicinal Chemical Biology, Department of Cell Biology and Genetics, College of Life Sciences, Nankai University, Tianjin 300071, China.
Renpeng GuoCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-2834-4086
Nanjing Agricultural University · CNKunming University of Science and Technology · CNNankai University · CN

Funding

Jiangsu Agricultural Science and Technology Innovative Fund CX(21)3043the National Natural Science Foundation of China 31900615, 32272468the Natural Science Foundation of Jiangsu Province BK20190511
6 · The paper itself

Abstract

Pluripotent embryonic stem cells (ESCs) can self-renew indefinitely and are able to differentiate into all three embryonic germ layers. Synaptosomal-associated protein 29 (Snap29) is implicated in numerous intracellular membrane trafficking pathways, including autophagy, which is involved in the maintenance of ESC pluripotency. However, the function of Snap29 in the self-renewal and differentiation of ESCs remains elusive. Here, we show that

Indexed as

Mouse Embryonic Stem CellsPluripotent Stem CellsAnimalsCell DifferentiationEmbryonic Stem CellsGene Expression ProfilingMiceQb-SNARE ProteinsQc-SNARE ProteinsQb-SNARE ProteinsQc-SNARE ProteinsSnap29 protein, mouseautophagyESCspluripotencySnap29

Identifiers

PMID36614195
PMCPMC9821219
OpenAlexW4313427564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.