Evidence map›Paper›PMID 36614140›Full record

ArticleInternational journal of molecular sciences2022

Inhibitory Mechanism of IL-6 Production by Orento in Oral Squamous Cell Carcinoma Cell Line CAL27 Stimulated by Pathogen-Associated Molecular Patterns from Periodontopathogenic

Yasuhiro Imamura, Yoshimasa Makita, Kazuya Masuno, Hourei Oh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Hangeshashinto InhibitsEvidence-based complementary and alternative medicine : eCAM · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yasuhiro ImamuraDepartment of Pharmacology, Matsumoto Dental University, Nagano 399-0781, Japan.
Yoshimasa MakitaDepartment of Chemistry, Osaka Dental University, Osaka 573-1121, Japan.ORCID 0000-0003-4732-8145
Kazuya MasunoCenter of Innovation in Dental Education, Osaka Dental University, Osaka 573-1121, Japan.
Hourei OhCenter of Innovation in Dental Education, Osaka Dental University, Osaka 573-1121, Japan.
Osaka Dental University · JPMatsumoto Dental University · JP

Funding

the Ministry of Education, Science, Sports and Culture, Grant-in-Aid for Scientific Research (C) 18K09929
6 · The paper itself

Abstract

Orento is a traditional Japanese medicinal kampo preparation that is also prescribed in oral care. In oral squamous cell carcinoma cell line CAL27, orento significantly inhibited periodontopathogenic bacterium

Indexed as

Mouth NeoplasmsSquamous Cell Carcinoma of Head and NeckCell Line, TumorHumansInterleukin-6LipopolysaccharidesNF-kappa BPathogen-Associated Molecular Pattern MoleculesPorphyromonas gingivalisToll-Like ReceptorsInterleukin-6LipopolysaccharidesNF-kappa BPathogen-Associated Molecular Pattern MoleculesToll-Like ReceptorsKampo medicineoral cancerorentoperiodontal diseasetoll-like receptor

Identifiers

PMID36614140
PMCPMC9821341
OpenAlexW4313473171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.