Evidence map›Paper›PMID 36614093›Full record

ReviewInternational journal of molecular sciences2022

The Role of

Ilka Jorde, Jens Schreiber, Sabine Stegemann-Koniszewski

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. ERJ open research · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Pathogens (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Article
  10. Staphylococcal enterotoxin B sensitization in eosinophilic asthma.The Korean journal of internal medicine · 2024
    Article
  11. Review
  12. Article
  13. Editorial of Special Issue "Molecular Mechanisms of Allergy and Asthma 2.0".International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ilka JordeExperimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Health Campus Immunology, Infectiology and Inflammation (GC-I3), Otto-von-Guericke-University, 39120 Magdeburg, Germany.
Jens SchreiberExperimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Health Campus Immunology, Infectiology and Inflammation (GC-I3), Otto-von-Guericke-University, 39120 Magdeburg, Germany.
Sabine Stegemann-KoniszewskiExperimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Health Campus Immunology, Infectiology and Inflammation (GC-I3), Otto-von-Guericke-University, 39120 Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DEUniversity Hospital Magdeburg · DE

Funding

Mitteldeutsche Gesellschaft für Pneumologie und Thoraxchirurgie 2019-MDGP-PA-001RTG 2408 361210922
6 · The paper itself

Abstract

Bronchial asthma is one of the most common chronic diseases worldwide and affects more than 300 million patients. Allergic asthma affects the majority of asthmatic children as well as approximately 50% of adult asthmatics. It is characterized by a Th2-mediated immune response against aeroallergens. Many aspects of the overall pathophysiology are known, while the underlying mechanisms and predisposing factors remain largely elusive today. Over the last decade, respiratory colonization with Staphylococcus aureus (S. aureus), a Gram-positive facultative bacterial pathogen, came into focus as a risk factor for the development of atopic respiratory diseases. More than 30% of the world’s population is constantly colonized with S. aureus in their nasopharynx. This colonization is mostly asymptomatic, but in immunocompromised patients, it can lead to serious complications including pneumonia, sepsis, or even death. S. aureus is known for its ability to produce a wide range of proteins including toxins, serine-protease-like proteins, and protein A. In this review, we provide an overview of the current knowledge about the pathophysiology of allergic asthma and to what extent it can be affected by different toxins produced by S. aureus. Intensifying this knowledge might lead to new preventive strategies for atopic respiratory diseases.

Indexed as

AsthmaHypersensitivity, ImmediateStaphylococcal InfectionsAdultAllergensChildEnterotoxinsHumansStaphylococcus aureusAllergensEnterotoxinsallergenallergic asthmaatopic diseasesmicrobial colonizationserine protease-like proteinstaphylococcal protein AStaphylococcus aureusStaphylococcus aureus enterotoxin Btoxic-shock-syndrome toxin 1toxin-specific IgE-sensitization

Identifiers

PMID36614093
PMCPMC9820472
OpenAlexW4313439641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.