Evidence map›Paper›PMID 36614058›Full record

ArticleInternational journal of molecular sciences2022

Ribosomal Stress Couples with the Hypoxia Response in Dec1-Dependent Orthodontic Tooth Movement.

Shigeru Nakamura, Keiji Tanimoto, Ujjal K Bhawal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Progress of Section "Biochemistry" in 2022.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shigeru NakamuraDepartment of Public and Preventive Dentistry, Nihon University Graduate School of Dentistry at Matsudo, Chiba 271-8587, Japan.
Keiji TanimotoDepartment of Translational Cancer Research, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.ORCID 0000-0003-4912-4197
Ujjal K BhawalDepartment of Pharmacology, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College, Chennai 600077, India.ORCID 0000-0002-3746-009X
Nihon University · JPHiroshima University · JP

Funding

Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan 21K10238Nihon University Multidisciplinary Research Grant for 2018 18-017
6 · The paper itself

Abstract

This study characterized the effects of a deficiency of the hypoxia-responsive gene, differentiated embryonic chondrocyte gene 1 (Dec1), in attenuating the biological function of orthodontic tooth movement (OTM) and examined the roles of ribosomal proteins in the hypoxic environment during OTM. HIF-1α transgenic mice and control mice were used for hypoxic regulation of periodontal ligament (PDL) fibroblasts.

Indexed as

Basic Helix-Loop-Helix ProteinsHomeodomain ProteinsHypoxiaTooth Movement TechniquesAnimalsHumansMiceMice, Inbred C57BLMice, TransgenicPeriodontal LigamentRibosomal ProteinsBasic Helix-Loop-Helix ProteinsBhlhe40 protein, mouseHomeodomain ProteinsRibosomal ProteinsDec1HIF-1αorthodontic tooth movementribosomal protein

Identifiers

PMID36614058
PMCPMC9820322
OpenAlexW4313571298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.