Evidence map›Paper›PMID 36614054›Full record

ArticleInternational journal of molecular sciences2022

Zhi-Han Lin, Shun-Ya Chang, Wen-Chi Shen, Yen-Hung Lin, Chiu-Lun Shen, Sin-Bo Liao, Yu-Chun Liu, Chang-Shi Chen, Tsui-Ting Ching, Horng-Dar Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Changes in the brain [NADFrontiers in aging neuroscience · 2026
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Zhi-Han LinInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Shun-Ya ChangInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Wen-Chi ShenInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Yen-Hung LinInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Chiu-Lun ShenDepartment of Life Science, National Tsing Hua University, Hsinchu 300044, Taiwan.
Sin-Bo LiaoInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Yu-Chun LiuInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Chang-Shi ChenDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Tsui-Ting ChingInstitute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0001-7650-1766
Horng-Dar WangInstitute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.ORCID 0000-0001-9570-3611
National Tsing Hua University · TWNational Taiwan University · TWNational Cheng Kung University · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology 106-2311-B-007-006-MY2, 108-2311-B-007-007-, 109-2311-B007-002-, 111-2320-B-007-006-MY3
6 · The paper itself

Abstract

Altered metabolism is a hallmark of aging. The tricarboxylic acid cycle (TCA cycle) is an essential metabolic pathway and plays an important role in lifespan regulation. Supplementation of α-ketoglutarate, a metabolite converted by

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsIsocitrate DehydrogenaseLongevityOxidative StressAnimalsCaenorhabditis elegans ProteinsIsocitrate DehydrogenaseC. elegansdietary restrictionidha-1longevityoxidative stressTCA cycleTOR pathway

Identifiers

PMID36614054
PMCPMC9820670
OpenAlexW4313578574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.