Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report.

Zi-Wei Chen, Gigin Lin, Hsuan-Jen Shih, Chiao-En Wu

Open access · goldAbstract readCase Reports

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 46% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zi-Wei ChenDepartment of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333423, Taiwan.ORCID 0000-0001-7904-2614

Gigin LinDepartment of Medical Imaging & Intervention, Clinical Metabolomics Core, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333423, Taiwan.ORCID 0000-0001-7246-1058

Hsuan-Jen ShihDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333423, Taiwan.

Chiao-En WuDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333423, Taiwan.ORCID 0000-0002-1081-8805

Chang Gung University · TW

Funding

Linkou Chang Gung Memorial Hospital CMRPG3M0971 to C-E.W. and CMRPG3K0601 to H.-J. S

6 · The paper itself

Abstract

Epidermal growth factor receptor (

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAcrylamidesAniline CompoundsDrug Resistance, NeoplasmErbB ReceptorsExonsFemaleHumansIndolesMutationOrganophosphorus CompoundsProtein Kinase InhibitorsPyrimidinesAcrylamidesAniline CompoundsbrigatinibErbB ReceptorsIndolesOrganophosphorus CompoundsosimertinibProtein Kinase InhibitorsPyrimidinesbrigatinibEGFR triple mutationEGFR-tyrosine kinase inhibitors resistanceNSCLCosimertinib resistanceT790M-cis-C797S

Identifiers

PMID36614045

DOI10.3390/ijms24010602

PMCPMC9820100

OpenAlexW4313361717

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.