ReviewInternational journal of molecular sciences2022
Existing and Novel Biomaterials for Bone Tissue Engineering.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unleashing innovation: 3D-printed biomaterials in bone tissue engineering for repairing femur and tibial defects in animal models - a systematic review and meta-analysis.Frontiers in bioengineering and biotechnology · 2024Pooled it
- Nano-engineering the titanium-tissue interface: a 15 year perspective on bio-functionalization and surface innovation.Nanoscale advances · 2026Review
- Advances in 3D Printed Bone Implants: Smart Responsive Antibacterial Strategies and AI-Driven Design.Biomimetics (Basel, Switzerland) · 2026Review
- Electrical stimulation as an emerging strategy in bone repair: Mechanisms, applications, and advances.Journal of orthopaedic translation · 2026Review
- Synchronizing degradation with regeneration: a model-driven framework for designing biodegradable biomaterials in bone tissue engineering.Journal of materials science. Materials in medicine · 2026Review
- From Nature to Innovation: Exploring Natural Biopolymers in 3D Bioprinting for Bone Regeneration.ACS omega · 2026Article
- Bone Fusion in the Cervical Spine: Where Are We Now?Bioengineering (Basel, Switzerland) · 2026Review
- Mussel-inspired adhesive hydrogel reprograms osteoimmune niche for robust bone regeneration in complex defects.Materials today. Bio · 2026Article
- Multifunctional implantable hydrogels: Smart platforms at the forefront of biomedical innovation.Materials today. Bio · 2026Review
- PRP-related biomaterials enhance bone and nerve repair.Materials today. Bio · 2026Review
- Treatment of femoral defects in rats with collagen and elastin polymers combined with hydroxyapatite and bone morphogenetic protein.Frontiers in bioengineering and biotechnology · 2026Article
- Stem cell-derived extracellular vesicles -mediated bone regeneration: mechanisms, targeted delivery, and clinical perspectives in promoting angiogenesis.Frontiers in bioengineering and biotechnology · 2026Review
- Editorial: Exploring the role of stem cells in bone health and regeneration.Frontiers in medicine · 2026Article
- Engineered mesenchymal stem cell-derived extracellular vesicles as programmable biomaterial platforms for liver fibrosis: design principles, manufacturing and clinical translation.Frontiers in bioengineering and biotechnology · 2026Review
- Potential of organ-on-a-chip in advancing synthetic extracellular matrix technology for bone tissue engineering in dentistry (Review).Biomedical reports · 2026Review
- Growth factor-free chondrogenesis and immunomodulation of Wharton's jelly MSCs on chitosan-hyaluronic acid films.Frontiers in bioengineering and biotechnology · 2026Article
- Three-Dimensional Printing of Calcium Phosphate-Mesoporous Bioactive Glass Scaffolds for Bone Tissue Engineering.Journal of functional biomaterials · 2025Article
- Current status, trend and progress of stem cells in tracheal tissue engineering research: an overview and perspectives.Stem cell research & therapy · 2025Review
- Advances in Titanium-Based Biomaterial for Human Bone Scaffolds: Narrative Review on Design, Fabrication, Surface Engineering, Implantation, and Biological Evaluation.Materials (Basel, Switzerland) · 2025Review
- From Autologous Bone Tissue to Bioengineered Material Solutions in Post-Traumatic Orbital Wall Reconstruction: An Overview.Journal of functional biomaterials · 2025Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of bone defects remains one of the major challenges in modern clinical practice. Nowadays, with the increased incidence of bone disease in an aging population, the demand for materials to repair bone defects continues to grow. Recent advances in the development of biomaterials offer new possibilities for exploring modern bone tissue engineering strategies. Both natural and synthetic biomaterials have been used for tissue repair. A variety of porous structures that promote cell adhesion, differentiation, and proliferation enable better implant integration with increasingly better physical properties. The selection of a suitable biomaterial on which the patient's new tissue will grow is one of the key issues when designing a modern tissue scaffold and planning the entire treatment process. The purpose of this article is to present a comprehensive literature review of existing and novel biomaterials used in the surgical treatment of bone tissue defects. The materials described are divided into three groups-organic, inorganic, and synthetic polymers-taking into account current trends. This review highlights different types of existing and novel natural and synthetic materials used in bone tissue engineering and their advantages and disadvantages for bone defects regeneration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.