Evidence map›Paper›PMID 36613936›Full record

ArticleInternational journal of molecular sciences2022

Ipconazole Disrupts Mitochondrial Homeostasis and Alters GABAergic Neuronal Development in Zebrafish.

Giyoung Lee, Amit Banik, Juneyong Eum, Byung Joon Hwang, Seung-Hae Kwon, Yun Kee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  8. Differential Neuroprotective Effects ofAntioxidants (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Giyoung LeeDepartment of Biomedical Science, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Amit BanikInterdisciplinary Graduate Program in Environmental and Biomedical Convergence, Kangwon National University, Chuncheon 24341, Republic of Korea.
Juneyong EumInterdisciplinary Graduate Program in Environmental and Biomedical Convergence, Kangwon National University, Chuncheon 24341, Republic of Korea.
Byung Joon HwangDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Seung-Hae KwonKorea Basic Science Institute Seoul Center, Seoul 02841, Republic of Korea.
Yun KeeDivision of Biomedical Convergence, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID 0000-0003-2764-1468
Kangwon National University · KRKorea Basic Science Institute · KR

Funding

Kangwon National University 2019 Research Grant (PoINT)Korean Basic Science Institute C220000Ministry of Education NRF-2020R1I1A3063583Ministry of Science and ICT NRF-2019M3C7A1031836
6 · The paper itself

Abstract

Ipconazole, a demethylation inhibitor of fungal ergosterol biosynthesis, is widely used in modern agriculture for foliar and seed treatment, and is authorized for use in livestock feed. Waste from ipconazole treatment enters rivers and groundwater through disposal and rain, posing potential toxicity to humans and other organisms. Its metabolites remain stable under standard hydrolysis conditions; however, their neurodevelopmental toxicity is unknown. We investigated the potential neurodevelopmental toxicity of ipconazole pesticides in zebrafish (

Indexed as

PesticidesWater Pollutants, ChemicalAnimalsAntioxidantsEmbryo, NonmammalianLarvaMitochondriaOxidative StressZebrafishAntioxidantsPesticidesWater Pollutants, Chemicalipconazole pesticidemitochondrial dysfunctionneurodevelopmental toxicityoxidative stresszebrafish

Identifiers

PMID36613936
PMCPMC9820214
OpenAlexW4313413677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.