Evidence map›Paper›PMID 36613926›Full record

ReviewInternational journal of molecular sciences2022

The γ-Core Motif Peptides of Plant AMPs as Novel Antimicrobials for Medicine and Agriculture.

Marina P Slezina, Ekaterina A Istomina, Tatyana V Korostyleva, Tatyana I Odintsova

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Broad-Spectrum Antimicrobial Potential of the γ-Core Motif Peptides ofInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Antifungal Peptides SmAPAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marina P SlezinaVavilov Institute of General Genetics RAS, 119333 Moscow, Russia.ORCID 0000-0003-1653-5993
Ekaterina A IstominaVavilov Institute of General Genetics RAS, 119333 Moscow, Russia.ORCID 0000-0001-6426-6009
Tatyana V KorostylevaVavilov Institute of General Genetics RAS, 119333 Moscow, Russia.
Tatyana I OdintsovaVavilov Institute of General Genetics RAS, 119333 Moscow, Russia.ORCID 0000-0002-5563-9755
Vavilov Institute of General Genetics · RU

Funding

Russian Science Foundation 22-16-00010
6 · The paper itself

Abstract

The γ-core motif is a structural element shared by most host antimicrobial peptides (AMPs), which is supposed to contribute to their antimicrobial properties. In this review, we summarized the available data on the γ-core peptides of plant AMPs. We describe γ-core peptides that have been shown to exhibit inhibitory activity against plant and human bacterial and fungal pathogens that make them attractive scaffolds for the development of novel anti-infective agents. Their advantages include origin from natural AMP sequences, broad-spectrum and potent inhibitory activity, and cost-effective production. In addition, some γ-core peptides combine antimicrobial and immunomodulatory functions, thus broadening the spectrum of practical applications. Some act synergistically with antimycotics and fungicides, so combinations of peptides with conventionally used antifungal agents can be suggested as an effective strategy to reduce the doses of potentially harmful chemicals. The presented information will pave the way for the design of novel antimicrobials on the basis of γ-core motif peptides, which can find application in medicine and the protection of crops from diseases.

Indexed as

Anti-Infective AgentsAntimicrobial PeptidesAgricultureAntifungal AgentsHumansPeptidesPlantsAntifungal AgentsAnti-Infective AgentsAntimicrobial PeptidesPeptidesantimicrobial activityantimicrobial peptides (AMPs)novel anti-infective agentsstructure-function relationshipsynthetic γ-core peptidesγ-core motif

Identifiers

PMID36613926
PMCPMC9820530
OpenAlexW4313414802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.