Evidence map›Paper›PMID 36613910›Full record

ArticleInternational journal of molecular sciences2022

Exosome-Based Cell Homing and Angiogenic Differentiation for Dental Pulp Regeneration.

Venkateswaran Ganesh, Dongrim Seol, Piedad C Gomez-Contreras, Henry L Keen, Kyungsup Shin, James A Martin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  9. Article
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  11. Advanced small extracellular vesicles delivery systems forExtracellular vesicles and circulating nucleic acids · 2026
    Review
  12. Review
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  14. Article
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  16. Article
  17. Article
  18. Isolation methods of exosomes derived from dental stem cells.International journal of oral science · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Venkateswaran GaneshDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-2776-7431
Dongrim SeolDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-0383-3756
Piedad C Gomez-ContrerasDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
Henry L KeenIowa Institute of Human Genetics, University of Iowa, Iowa City, IA 52242, USA.
Kyungsup ShinDepartment of Orthodontics, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-1064-8735
James A MartinDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.

Funding

Exosome-based Cell Homing and Lineage-Specific Differentiation Strategies for Dental Pulp RegenerationR03DE030515 · NIDCR · UNIVERSITY OF IOWA · PI SEOL, DONG RIM · 2021 to 2022
$303k
NIDCR NIH HHS 1R03DE030515-01NIDCR NIH HHS R03 DE030515
6 · The paper itself

Abstract

Exosomes have attracted attention due to their ability to promote intercellular communication leading to enhanced cell recruitment, lineage-specific differentiation, and tissue regeneration. The object of this study was to determine the effect of exosomes on cell homing and angiogenic differentiation for pulp regeneration. Exosomes (DPSC-Exos) were isolated from rabbit dental pulp stem cells cultured under a growth (Exo-G) or angiogenic differentiation (Exo-A) condition. The characterization of exosomes was confirmed by nanoparticle tracking analysis and an antibody array. DPSC-Exos significantly promoted cell proliferation and migration when treated with 5 × 10

Indexed as

ExosomesVascular Endothelial Growth Factor AAnimalsCell DifferentiationCell ProliferationDental PulpNeovascularization, PhysiologicRabbitsRegenerationVascular Endothelial Growth Factor Aangiogenesiscell homingdental pulp stem cellsexosomesmicroRNA profilepulp regeneration

Identifiers

PMID36613910
PMCPMC9820194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.