Evidence map›Paper›PMID 36613889›Full record

ArticleInternational journal of molecular sciences2022

Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis.

Ina Ćorković, Aleš Rajchl, Tereza Škorpilová, Anita Pichler, Josip Šimunović, Mirela Kopjar

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ina ĆorkovićFaculty of Food Technology, Josip Juraj Strossmayer University, F. Kuhača 18, 31000 Osijek, Croatia.ORCID 0000-0002-4478-5431
Aleš RajchlDepartment of Food Preservation, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 3, Dejvice, 166 28 Prague, Czech Republic.
Tereza ŠkorpilováDepartment of Food Preservation, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 3, Dejvice, 166 28 Prague, Czech Republic.
Anita PichlerFaculty of Food Technology, Josip Juraj Strossmayer University, F. Kuhača 18, 31000 Osijek, Croatia.ORCID 0000-0002-5437-9111
Josip ŠimunovićDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695-7624, USA.
Mirela KopjarFaculty of Food Technology, Josip Juraj Strossmayer University, F. Kuhača 18, 31000 Osijek, Croatia.ORCID 0000-0001-6864-4652
University of Osijek · HRUniversity of Chemistry and Technology, Prague · CZNorth Carolina State University · US

Funding

Hrvatska Zaklada za Znanost IP-2019- 04-5749
6 · The paper itself

Abstract

With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise. Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible for antioxidant activity and other positive effects on human health. However, other natural food ingredients, such as disaccharides, can affect their stability. The aim of this study was to investigate the influence of disaccharides addition on the polyphenol composition of chokeberry hydrogels. Hydrogels were prepared from chokeberry juice and 2% of carboxymethylcellulose (CMC) with the addition of 30%, 40%, or 50% of disaccharides (sucrose or trehalose). Samples were analyzed using DART-TOF/MS. The method was optimized, and the fingerprints of the mass spectra have been statistically processed using PCA analysis. Prepared samples were evaluated for total polyphenols, monomeric anthocyanins, and antioxidant activity (FRAP, CUPRAC, DPPH, ABTS assays) using spectrophotometric methods. Individual polyphenols were evaluated using HPLC-DAD analysis. Results showed the addition of disaccharides to 2% CMC hydrogels caused a decrease of total polyphenols. These findings confirm proper formulation is important to achieve appropriate retention of polyphenols.

Indexed as

AntioxidantsCarboxymethylcellulose SodiumAnthocyaninsChromatography, High Pressure LiquidDisaccharidesFruitHumansPlant ExtractsPolyphenolsAnthocyaninsAntioxidantsCarboxymethylcellulose SodiumDisaccharidesPlant ExtractsPolyphenolscarboxymethylcellulose hydrogelschokeberryDARTdisaccharidesHPLCpolyphenols

Identifiers

PMID36613889
PMCPMC9820810
OpenAlexW4312223254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.