SynthesisInternational journal of molecular sciences2022
The Diagnostic Performance of Ultrasonography in the Evaluation of Extrathyroidal Extension in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Synthesis in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The evolving role of MRI in the detection of extrathyroidal extension of papillary thyroid carcinoma: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Diagnostic performance and generalizability of a clinical-ultrasound radiomics model for predicting extrathyroidal extension in thyroid carcinoma: a retrospective study.Annals of medicine · 2026Article
- Article
- A multimodal study on predicting extrathyroidal extension of papillary thyroid carcinoma based on radiopathomics.BMC endocrine disorders · 2026Article
- Discovery and validation of PARP4 methylation in distinguishing thyroid cancer from benign nodule.Journal of endocrinological investigation · 2026Article
- Diagnostic performance of ultrasonography in predicting extrathyroidal extension in papillary thyroid carcinoma.BMC medical imaging · 2026Article
- MRI-based model to predict preoperative extrathyroidal extension in papillary thyroid carcinoma.European radiology · 2025Article
- Prediction model for extrathyroidal extension in thyroid papillary carcinoma based on ultrasound radiomics.Scientific reports · 2025Article
- Ultrasound feature-based nomogram model for predicting extrathyroidal extension in papillary thyroid carcinoma.BMC cancer · 2025Article
- Systems biology approach delineates critical pathways associated with papillary thyroid cancer: a multi-omics data analysis.Thyroid research · 2025Article
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- New Trends in Pathology: From Cell Morphology to Molecular Medicine.International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Extrathyroidal extension (ETE) in patients with papillary thyroid carcinoma (PTC) is an indication of disease progression and can influence treatment aggressiveness. This meta-analysis assesses the diagnostic accuracy of ultrasonography (US) in detecting ETE. A systematic review and meta-analysis were performed by searching PubMed, Embase, and Cochrane for studies published up to April 2022. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) were calculated. The areas under the curve (AUC) for summary receiver operating curves were compared. A total of 11 studies analyzed ETE in 3795 patients with PTC. The sensitivity of ETE detection was 76% (95%CI = 74-78%). The specificity of ETE detection was 51% (95%CI = 49-54%). The DOR of detecting ETE by US was 5.32 (95%CI = 2.54-11.14). The AUC of ETE detection was determined to be 0.6874 ± 0.0841. We report an up-to-date analysis elucidating the diagnostic accuracy of ETE detection by US. Our work suggests the diagnostic accuracy of US in detecting ETE is adequate. Considering the importance of ETE detection on preoperative assessment, ancillary studies such as adjunct imaging studies and genetic testing should be considered.
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