Evidence map›Paper›PMID 36613752›Full record

ArticleInternational journal of molecular sciences2022

Role of Thylakoid Lipids in Protochlorophyllide Oxidoreductase Activation: Allosteric Mechanism Elucidated by a Computational Study.

Ruiyuan Liu, Leng Wang, Yue Meng, Fang Li, Haiyu Nie, Huizhe Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruiyuan LiuCollege of Science, China Agricultural University, Beijing 100193, China.
Leng WangCollege of Science, China Agricultural University, Beijing 100193, China.
Yue MengCollege of Science, China Agricultural University, Beijing 100193, China.
Fang LiCollege of Science, China Agricultural University, Beijing 100193, China.
Haiyu NieCollege of Science, China Agricultural University, Beijing 100193, China.
Huizhe LuCollege of Science, China Agricultural University, Beijing 100193, China.
China Agricultural University · CN

Funding

National Natural Science Foundation of China 21873115
6 · The paper itself

Abstract

Light-dependent protochlorophyllide oxidoreductase (LPOR) is a chlorophyll synthetase that catalyzes the reduction of protochlorophyllide (Pchlide) to chlorophyllide (Chlide) with indispensable roles in regulating photosynthesis processes. A recent study confirmed that thylakoid lipids (TL) were able to allosterically enhance modulator-induced LPOR activation. However, the allosteric modulation mechanism of LPOR by these compounds remains unclear. Herein, we integrated multiple computational approaches to explore the potential cavities in the

Indexed as

ArabidopsisOxidoreductases Acting on CH-CH Group DonorsChlorophyllLightLipidsNADPOxidoreductasesProtochlorophyllideThylakoidsChlorophyllLipidsNADPOxidoreductasesOxidoreductases Acting on CH-CH Group DonorsProtochlorophyllideallosteric modulationlight-dependent protochlorophyllide oxidoreductasemolecular dynamics simulationthylakoid lipids

Identifiers

PMID36613752
PMCPMC9820216
OpenAlexW4313260781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.