Evidence map›Paper›PMID 36613733›Full record

ArticleInternational journal of molecular sciences2022

Age- and Lifespan-Dependent Differences in GO Caused DNA Damage in

Barbara Flasz, Marta Dziewięcka, Amrendra K Ajay, Monika Tarnawska, Agnieszka Babczyńska, Andrzej Kędziorski, Łukasz Napora-Rutkowski, Patrycja Ziętara, Ewa Świerczek, Maria Augustyniak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Evaluation of Molecular Responses and Longevity Markers inInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Barbara FlaszInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.
Marta DziewięckaInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.ORCID 0000-0001-9321-2579
Amrendra K AjayDepartment of Medicine, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-2790-5726
Monika TarnawskaInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.
Agnieszka BabczyńskaInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.ORCID 0000-0002-0000-789X
Andrzej KędziorskiInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.
Łukasz Napora-RutkowskiPolish Academy of Sciences, Institute of Ichthyobiology and Aquaculture in Gołysz, 43-520 Chybie, Poland.
Patrycja ZiętaraInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.
Ewa ŚwierczekInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.
Maria AugustyniakInstitute of Biology, Biotechnology and Environmental Protection, University of Silesia in Katowice, 40-007 Katowice, Poland.ORCID 0000-0003-1960-1669
University of Silesia in Katowice · PLBrigham and Women's Hospital · USPolish Academy of Sciences · PL

Funding

National Science Center (NCN) in Poland UMO-2020/37/B/NZ7/00570Research Excellence Initiative of the University of Silesia in Katowice POB5
6 · The paper itself

Abstract

The rising applicability of graphene oxide (GO) should be preceded by detailed tests confirming its safety and lack of toxicity. Sensitivity to GO of immature, or with different survival strategy, individuals has not been studied so far. Therefore, in the present research, we focused on the GO genotoxic effects, examining selected parameters of DNA damage (total DNA damage, double-strand breaks-DSB, 8-hydroxy-2'-deoxyguanosine-8-OHdG, abasic site-AP sites), DNA damage response parameters, and global methylation in the model organism

Indexed as

GraphiteLongevity8-Hydroxy-2'-DeoxyguanosineDNA DamageDNA RepairHumans8-Hydroxy-2'-Deoxyguanosinegraphene oxideGraphite8-OHdGAP sitescarbon nanoparticlesDSBGlobal DNA methylationinsectspATMpH2A.Xtotal DNA damage

Identifiers

PMID36613733
PMCPMC9820743
OpenAlexW4313244866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.