Evidence map›Paper›PMID 36613721›Full record

ArticleInternational journal of molecular sciences2022

The Flavonoid Naringenin Alleviates Collagen-Induced Arthritis through Curbing the Migration and Polarization of CD4

Yue-Peng Jiang, Jun-Jun Wen, Xiao-Xuan Zhao, Yuan-Cheng Gao, Xiao Ma, Si-Yue Song, Yan Jin, Tie-Juan Shao, Jie Yu, Cheng-Ping Wen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Biochemistry and biophysics reports · 2026
    Article
  3. Modulation of Cognitive Function by TRPM3 Channels in the Dentate Gyrus of a Menopausal Rat Model: Effects of Naringenin Treatment and Ciliary Neurotrophic Factor.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yue-Peng JiangCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jun-Jun WenKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xiao-Xuan ZhaoKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yuan-Cheng GaoKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xiao MaKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Si-Yue SongKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yan JinKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Tie-Juan ShaoKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jie YuCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID 0000-0002-6768-7236
Cheng-Ping WenCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a progressive autoimmune disease. Due to local infiltration and damage to the joints, activated CD4

Indexed as

Arthritis, ExperimentalArthritis, RheumatoidAnimalsCD4-Positive T-LymphocytesFlavanonesFlavonoidsMitochondrial DynamicsPainRatsFlavanonesFlavonoidsnaringeninCD4+ T lymphocytescollagen-induced arthritismigrationmitochondrial fissionpolarizationrheumatoid arthritis

Identifiers

PMID36613721
PMCPMC9820519
OpenAlexW4313244472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.