Evidence map›Paper›PMID 36613648›Full record

ArticleInternational journal of molecular sciences2022

Determination of BRCAness Phenotype in Breast Tumors for the Appointment of Neoadjuvant Chemotherapy Based on Platinum and Taxanes.

Matvey Mihajlovich Tsyganov, Marina K Ibragimova, Evgeniy Y Garbukov, Olga D Bragina, Ariana A Karchevskaya, Evgeny A Usynin, Nikolai V Litvyakov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Mutations ofGenes · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matvey Mihajlovich TsyganovDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.
Marina K IbragimovaDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.
Evgeniy Y GarbukovDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.
Olga D BraginaDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.
Ariana A KarchevskayaFaculty of Medicine and Biology, Siberian State Medical University, 2 Moskovsky Trakt, Tomsk 634050, Russia.
Evgeny A UsyninDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.
Nikolai V LitvyakovDepartment of Experimental Oncology, Research Institute of Oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences, St. Kooperativny 5, Tomsk 634009, Russia.ORCID 0000-0002-0714-8927
Russian Academy of Sciences · RUSiberian State Medical University · RU

Funding

Russian Science Foundation 22-15-00169
6 · The paper itself

Abstract

The concept of BRCAness was developed because of similarities between sporadic and hereditary breast cancer. BRCAness defines the pathogenesis and treatment sensitivity of many types of cancer, as well as the presence of a defect in the homologous recombination repair of tumor cells simulating the loss of

Indexed as

Breast NeoplasmsBRCA1 ProteinBRCA2 ProteinFemaleHumansNeoadjuvant TherapyPhenotypePlatinumProspective StudiesTaxoidsBRCA1 ProteinBRCA2 ProteinPlatinumTaxoidsBRCAnessbreast cancerDNA copy number aberrationgene expressionhomologous recombinationhomologous recombination deficiencyloss of heterozygositymicroarray analysisneoadjuvant chemotherapypersonalized treatment

Identifiers

PMID36613648
PMCPMC9820727
OpenAlexW4312175798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.