Evidence map›Paper›PMID 36613618›Full record

ArticleInternational journal of molecular sciences2022

Late-Stage Functionalization through Click Chemistry Provides GLUT5-Targeting Glycoconjugate as a Potential PET Imaging Probe.

Adelina Oronova, Marina Tanasova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. GLUT5-overexpression-related tumorigenic implications.Molecular medicine (Cambridge, Mass.) · 2024
    Review
  4. GLUT5: structure, functions, diseases and potential applications.Acta biochimica et biophysica Sinica · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adelina OronovaChemistry Department, Michigan Technological University, Houghton, MI 49931, USA.ORCID 0000-0002-4918-5013
Marina TanasovaChemistry Department, Michigan Technological University, Houghton, MI 49931, USA.ORCID 0000-0003-4771-9533
Michigan Technological University · US

Funding

Molecular probes for targeting facilitative fructose transporters (GLUTs) in biochemical and biomedical applicationsR15CA242401 · NCI · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI TANASOVA, MARINA · 2019 to 2024
$902k
NCI NIH HHS R15 CA242401NIH HHS GRANT12736422
6 · The paper itself

Abstract

The targeting of facilitative sugar transporters (GLUTs) has been utilized in the development of tools for diagnostics and therapy. The interest in this area is promoted by the phenomenon of alterations in cellular metabolic processes that are linked to multitudes of metabolic disorders and diseases. However, nonspecific targeting (e.g., glucose-transporting GLUTs) leads to a lack of disease detection efficiency. Among GLUTs, GLUT5 stands out as a prominent target for developing specific molecular tools due to its association with metabolic diseases, including cancer. This work reports a non-radiolabeled fluoride (

Indexed as

Click ChemistryFructoseBiological TransportCell Line, TumorHumansPositron-Emission TomographyFructosecancer imagingclick chemistryfructose transportGLUTsglycoconjugatesPET imagingsugar–disease connectionsugar transport

Identifiers

PMID36613618
PMCPMC9820411
OpenAlexW4312187491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.