Evidence map›Paper›PMID 36613569›Full record

ReviewInternational journal of molecular sciences2022

Diagnosis by Volatile Organic Compounds in Exhaled Breath in Exhaled Breath from Patients with Gastric and Colorectal Cancers.

Jinwook Chung, Salima Akter, Sunhee Han, Yoonhwa Shin, Tae Gyu Choi, Insug Kang, Sung Soo Kim

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620743 (Key Technology Research on Non-invasive Early Diagnosis of Colorectal Cancer Based on Odor-targeted Capture, Instant Detection, and Intelligent Analysis), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07620743 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Key Technology Research on Non-invasive Early Diagnosis of Colorectal Cancer Based on Odor-targeted Capture, Instant Detection, and Intelligent Analysis

TypeobservationalSponsorBeijing University of Chinese MedicineRan2026 to 2029Enrolled453ConditionsCRC, Precancerous Condition, Healthy
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinwook ChungBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.
Salima AkterDepartment of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Sunhee HanBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.
Yoonhwa ShinBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.
Tae Gyu ChoiBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.
Insug KangBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0001-7117-1008
Sung Soo KimBiomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea.
Kyung Hee University · KR

Funding

National Research Foundation of Korea NRF-2018R1A6A1A03025124National Research Foundation of Korea NRF- 2020R1I1A1A01069013
6 · The paper itself

Abstract

One in three cancer deaths worldwide are caused by gastric and colorectal cancer malignancies. Although the incidence and fatality rates differ significantly from country to country, the rates of these cancers in East Asian nations such as South Korea and Japan have been increasing each year. Above all, the biggest danger of this disease is how challenging it is to recognize in its early stages. Moreover, most patients with these cancers do not present with any disease symptoms before receiving a definitive diagnosis. Currently, volatile organic compounds (VOCs) are being used for the early prediction of several other diseases, and research has been carried out on these applications. Exhaled VOCs from patients possess remarkable potential as novel biomarkers, and their analysis could be transformative in the prevention and early diagnosis of colon and stomach cancers. VOCs have been spotlighted in recent studies due to their ease of use. Diagnosis on the basis of patient VOC analysis takes less time than methods using gas chromatography, and results in the literature demonstrate that it is possible to determine whether a patient has certain diseases by using organic compounds in their breath as indicators. This study describes how VOCs can be used to precisely detect cancers; as more data are accumulated, the accuracy of this method will increase, and it can be applied in more fields.

Indexed as

Colorectal NeoplasmsStomach NeoplasmsVolatile Organic CompoundsBiomarkersBreath TestsExhalationGas Chromatography-Mass SpectrometryHumansBiomarkersVolatile Organic Compoundsearly diagnosisgastric and colorectal cancermass spectroscopyvolatile organic compounds

Identifiers

PMID36613569
PMCPMC9820758
OpenAlexW4313505587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.