Evidence map›Paper›PMID 36613525›Full record

Trial reportInternational journal of molecular sciences2022

Hepato-Protective Effects of Delta-Tocotrienol and Alpha-Tocopherol in Patients with Non-Alcoholic Fatty Liver Disease: Regulation of Circulating MicroRNA Expression.

Muhammad Amjad Pervez, Dilshad Ahmed Khan, Sayed Tanveer Abbas Gilani, Safia Fatima, Aamir Ijaz, Sumbal Nida

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Muhammad Amjad PervezArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.ORCID 0000-0001-8562-4733
Dilshad Ahmed KhanArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.
Sayed Tanveer Abbas GilaniArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.ORCID 0000-0001-9432-1435
Safia FatimaArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.
Aamir IjazArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.ORCID 0000-0002-0190-0081
Sumbal NidaArmed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.
Armed Forces Institute of Pathology · PK

Funding

National University of Medical Sciences 43/Accts/NUMS/2019
6 · The paper itself

Abstract

MicroRNAs (miRNAs) play a key role in the regulation of genes for normal metabolism in the liver. Dysregulation of miRNAs is involved in the development and progression of non-alcoholic fatty liver disease (NAFLD). We aimed to explore changes in circulating miRNA expression in response to delta-tocotrienol (δT3) and alpha-tocopherol (αTF) supplementation and correlate them with relevant biochemical markers in patients with NAFLD. In total, 100 patients with NAFLD were randomized to either receive δT3 (

Indexed as

Circulating MicroRNAInsulin ResistanceMicroRNAsNon-alcoholic Fatty Liver Diseasealpha-TocopherolBiomarkersHumansInflammationLiverVitamin Ealpha-TocopherolBiomarkersCirculating MicroRNAMicroRNAsMIRN122 microRNA, humantocotrienol, deltaVitamin Eapoptosiscirculating microRNAsinflammationnon-alcoholic fatty liver diseaseα-tocopherolδ-tocotrienol

Identifiers

PMID36613525
PMCPMC9820400
OpenAlexW4313468737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.